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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Characterization of the antifungal and antiprotozoal antibiotic partricin and structural studies on partricins A and B.

Partricin, a heptaene macrolide antibiotic, has been separated into three polyene components, partricins A, B and C, and one non-polyene component by countercurrent distribution. Treatment of partricin with base gave p-(methylamino)acetophenone and p-aminoacetophenone from partricins A and B, respectively, identifying both as members of the aromatic subgroup of the heptaene antibiotics. Both partricins A and B yield mycosamine on mild acid hydrolysis. NMR and mass spectral studies on products of ozonolysis or hydrogenolysis of acetyl derivatives provided evidence for the partial structures 1 approximately 9.[1]

References

  1. Characterization of the antifungal and antiprotozoal antibiotic partricin and structural studies on partricins A and B. Tweit, R.C., Pandey, R.C., Rinehart, K.L. J. Antibiot. (1982) [Pubmed]
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