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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Susceptibility of Haemophilus influenzae type b to cefaclor and influence of inoculum size.

Cefaclor appeared to be an effective antibiotic against both beta-lactamase-positive and beta-lactamase-negative strains of Haemophilus influenzae type b when tested with 10(5) colony-forming units per ml. With inocula in excess of 10(6) colony-forming units per ml, these organisms were neither inhibited nor killed at concentrations of 400 micrograms/ml. This inoculum effect was also demonstrated in time-kill curve studies.[1]

References

  1. Susceptibility of Haemophilus influenzae type b to cefaclor and influence of inoculum size. Levin, R.M., Azimi, P.H., Dunphy, M.G. Antimicrob. Agents Chemother. (1982) [Pubmed]
 
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