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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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The mutagenic activity of ethyl N-hydroxycarbamate and its related compounds in Salmonella typhimurium.

Alkyl N-hydroxycarbamates exhibited weak but significant mutagenic activity for Salmonella typhimurium TA100. The mutagenic potencies of these N-hydroxycarbamates were ranked thus: ethyl N-hydroxycarbamate greater than propyl N-hydroxycarbamate greater than methyl N-hydroxycarbamate. Acylation of ethyl N-hydroxycarbamate markedly enhanced its mutagenic activity for TA100. The highest mutagenic activity was observed with ethyl N-benzoyloxycarbamate among these acyl derivatives. Almost all the compounds were mutagenic to all the strains TA1535, TA100, TA98, especially to TA100.[1]

References

  1. The mutagenic activity of ethyl N-hydroxycarbamate and its related compounds in Salmonella typhimurium. Koga, H., Kawazoe, Y., Tatsumi, K., Horiuchi, T. Mutat. Res. (1980) [Pubmed]
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