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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Structure of the neuraminidase gene in human influenza virus A/PR/8/34.

The complete structure of the neuraminidase gene in influenza A/PR/8/34 has been determined by cloning into the bacteriophage M13 and sequencing with dideoxynucleotide chain terminators. The gene is 1,413 nucleotides long, codes for a protein of 454 amino acids and has five potential glycosylation sites. We suggest that the neuraminidase, unlike the influenza haemagglutinin, is oriented with its N-terminus buried in the viral membrane.[1]


  1. Structure of the neuraminidase gene in human influenza virus A/PR/8/34. Fields, S., Winter, G., Brownlee, G.G. Nature (1981) [Pubmed]
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