The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Effects of retinoids on plating efficiency, sister-chromatid exchange (SCE) and mitomycin-C-induced SCE in cultured Chinese hamster cells.

The effects of 5 retinoids, namely, all-trans-retinol (ROL), all-trans-retinoic acid (RA), all-trans-retinal (RAL), all-trans-retinyl acetate (RAc), and Ro. 10-9359-TMMP ethyl retinoate on plating efficiency, sister-chromatid exchange (SCE) and on mitomycin-C (MMC)-induced SCE were studied in Chinese hamster V79 cells. All the retinoids caused reduction of plating efficiency in a dose-dependent manner but the degree of plating efficiency reduction varied considerably among the retinoids studies. RAL was the most potent reducer of plating efficiency and this was followed in decreasing order by ROL, RAc, RA and Ro. 10-9359. For the effect of various doses of retinoids on SCE, it was clearly demonstrated that addition of each of the 5 retinoids to exponentially growing V79 cells had no significant effect on SCE frequency as compared to the controls. Besides this, these compounds did not alter DCS frequency induced by MMC.[1]


WikiGenes - Universities