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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Contact urticaria and asthma from denatonium benzoate (Bitrex).

A 30-year-old male developed asthma and pruritus after using an insecticidal spray (Pyrex). The same symptoms appeared with an alcoholic skin disinfectant (M-sprit) and other spirituous preparations denaturated with denatonium benzoate (Bitrex). An open epicutaneous test (20 min) showed wheal and erythema to Pyrex, M-sprit and Bitrex diluted to 2 x 10(-6) mg 1-1. It is deduced that the contact urticaria elicited from denatonium benzoate was caused by an immunologic mechanism of the immediate hypersensitivity type.[1]

References

  1. Contact urticaria and asthma from denatonium benzoate (Bitrex). Björkner, B. Contact Derm. (1980) [Pubmed]
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