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Thust, R. et al.

Clastogenicity and aberration kinetics of some alkylarylnitrosoureas in Chinese hamster V79-E cells.

Six alkylarylnitrosoureas were checked for induction of chromosome aberrations and SCEs in Chinese hamster V79-E cells and compared with MNU, ENU and nitrosocarbaryl. All agents show a DNA-damaging activity. Studies of the dependence of aberration frequency on recovery time revealed drastic differences within this group of closely related substances.[1]

References

Clastogenicity and aberration kinetics of some alkylarylnitrosoureas in Chinese hamster V79-E cells. Thust, R., Mendel, J., Schwarz, H., Warzok, R. IARC Sci. Publ. (1980) [Pubmed]

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