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Chemical Compound Review

Nitroso-nac     naphthalen-1-yl N-methyl-N-nitroso-carbamate

Synonyms: CCRIS 1217, AG-G-40484, AC1L2MGK, LS-50304, CTK5C0843, ...
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Disease relevance of Nitrosocarbaryl


High impact information on Nitrosocarbaryl


Biological context of Nitrosocarbaryl


Anatomical context of Nitrosocarbaryl


Gene context of Nitrosocarbaryl

  • Nitrosocarbaryl inhibited epoxide hydrolase activity gradually up to 18% at the range of concentration studied (1.3 X 10(-3) M - 1.2 X 10(-2) M) and showed a significant (P less than 0.001) inhibition at the concentration of 1.2 X 10(-2) M [8].

Analytical, diagnostic and therapeutic context of Nitrosocarbaryl


  1. Effects of nitrosocarbaryl on BALB/3T3 cells. Quarles, J.M., Tennant, R.W. Cancer Res. (1975) [Pubmed]
  2. N-Nitrosocarbaryl-induced mutagenesis in Haemophilus influenzae strains deficient in repair and recombination. Beattie, K.L. Mutat. Res. (1975) [Pubmed]
  3. Inhibition of two rat hepatic microsomal drug-metabolizing enzymes by a carcinogenic N-nitrosated pesticide: N-nitrosocarbaryl. Beraud, M., Gaillard, S., Derache, R. Chem. Biol. Interact. (1980) [Pubmed]
  4. Expression of transformation in cell hybrids. II. Nonsuppression of the transformed phenotype in hybrids between a chemically transformed and nontransformed derivatives of Balb/3T3. Jha, K.K., Cacciapuoti, J., Ozer, H.L. J. Cell. Physiol. (1978) [Pubmed]
  5. Evidence that UV-inducible error-prone repair is absent in Haemophilus influenzae Rd, with a discussion of the relation to error-prone repair of alkylating-agent damage. Kimball, R.F., Boling, M.E., Perdue, S.W. Mutat. Res. (1977) [Pubmed]
  6. Lipid peroxidation in rat liver microsomes: influence of carcinogenic N-nitrosocarbaryl. Beraud, M., Forgue, M.F., Pipy, B., Didier, A., Carre, P. Toxicology (1989) [Pubmed]
  7. Clastogenicity and aberration kinetics of some alkylarylnitrosoureas in Chinese hamster V79-E cells. Thust, R., Mendel, J., Schwarz, H., Warzok, R. IARC Sci. Publ. (1980) [Pubmed]
  8. Comparison of nitrosocarbaryl and carbaryl: in vitro effects on hepatic microsomal aryl hydrocarbon hydroxylase, aminopyrine N-demethylase, epoxide hydrolase and cytosolic glutathione-S-transferase. Chan, H.H., Buhler, D.R. Proc. Natl. Sci. Counc. Repub. China B (1984) [Pubmed]
  9. Distribution of radioactivity following oral administration of carcinogenic 14CH3-labelled nitrosocarbaryl in the rat. Beraud, M., Gaillard, D., Pipy, B., Derache, R. Cancer Lett. (1981) [Pubmed]
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