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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Effect of an inhaled corticosteroid on methacholine airway reactivity.

Methacholine airway reactivity was studied in seven asthmatic patients before and at the end of 4 mo of beclomethasone dipropionate therapy, as well as in a control group. There was no statistically significant change in reactivity in either group, suggesting that a change in airway cholinergic receptor activity is not part of the mechanism of action of corticosteroids in asthma.[1]


  1. Effect of an inhaled corticosteroid on methacholine airway reactivity. Easton, J.G. J. Allergy Clin. Immunol. (1981) [Pubmed]
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