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Chemical Compound Review

AGN-PC-00YNHO     [2-(9-chloro-11-hydroxy- 10,13,16-trimethyl...

Synonyms: SureCN2404673, KBioGR_000652, KBioSS_000468, CCG-40328, NINDS_000839, ...
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Psychiatry related information on BECLOMETHASONE DIPROPIONATE


High impact information on BECLOMETHASONE DIPROPIONATE


Chemical compound and disease context of BECLOMETHASONE DIPROPIONATE



  • In this study, we examined the effect of inhaled beclomethasone dipropionate (BDP) on bone mineral density (BMD) and biochemical markers of bone metabolism in pre- and early postmenopausal asthmatic women [16].
  • Thus, early postmenopausal, but not premenopausal, asthmatic patients who were treated with inhaled BDP had reduced BMD, which was associated with a decreased level of the bone formation marker [16].
  • Fluticasone propionate (FP) is a new ICS with a higher clinical potency than beclomethasone dipropionate (BDP) combined with negligible oral bioavailability [17].
  • Six-minute walk test results and sputum analysis for cell count and differential were not significantly different during placebo and BDP treatment periods [18].
  • Inflammatory indexes in induced sputum, exhaled nitric oxide levels, and vascular permeability index were examined in 11 normal control subjects, 19 beclomethasone dipropionate (BDP)-treated subjects with asthma, 20 non-BDP-treated subjects with asthma, and 17 patients with eosinophilic bronchitis [19].



Associations of BECLOMETHASONE DIPROPIONATE with other chemical compounds




Analytical, diagnostic and therapeutic context of BECLOMETHASONE DIPROPIONATE


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  2. High-dose beclomethasone inhaler in the treatment of asthma. Smith, M.J., Hodson, M.E. Lancet (1983) [Pubmed]
  3. Oral beclomethasone dipropionate for treatment of intestinal graft-versus-host disease: a randomized, controlled trial. McDonald, G.B., Bouvier, M., Hockenbery, D.M., Stern, J.M., Gooley, T., Farrand, A., Murakami, C., Levine, D.S. Gastroenterology (1998) [Pubmed]
  4. Coating of oral beclomethasone dipropionate capsules with cellulose acetate phthalate enhances delivery of topically active antiinflammatory drug to the terminal ileum. Levine, D.S., Raisys, V.A., Ainardi, V. Gastroenterology (1987) [Pubmed]
  5. Beclomethasone dipropionate enemas for treating inflammatory bowel disease without producing Cushing's syndrome or hypothalamic pituitary adrenal suppression. Kumana, C.R., Seaton, T., Meghji, M., Castelli, M., Benson, R., Sivakumaran, T. Lancet (1982) [Pubmed]
  6. Twice daily beclomethasone dipropionate administered with a concentrated aerosol inhaler: efficacy and patient compliance. Smith, M.J., Hodson, M.E. Thorax (1986) [Pubmed]
  7. Beclomethasone dipropionate aerosol: patient consultation recommendations. Fischer, R.G., Kuhn, J.G. Drug intelligence & clinical pharmacy. (1979) [Pubmed]
  8. Suppression of pituitary-adrenal axis in children on beclomethasone dipropionate inhalation therapy. Pijls, N.H., Driessen, M.N. Lancet (1984) [Pubmed]
  9. Inhaled therapy reduces morning dips in asthma. Horn, C.R., Clark, T.J., Cochrane, G.M. Lancet (1984) [Pubmed]
  10. Beclomethasone diproprionate for severe asthma during pregnancy. Greenberger, P.A., Patterson, R. Ann. Intern. Med. (1983) [Pubmed]
  11. Fluticasone propionate given once daily is as effective for seasonal allergic rhinitis as beclomethasone dipropionate given twice daily. Ratner, P.H., Paull, B.R., Findlay, S.R., Hampel, F., Martin, B., Kral, K.M., Rogenes, P.R. J. Allergy Clin. Immunol. (1992) [Pubmed]
  12. A comparison of the effects of sodium cromoglycate and beclomethasone dipropionate on pulmonary function and bronchial hyperreactivity in subjects with asthma. Svendsen, U.G., Frølund, L., Madsen, F., Nielsen, N.H., Holstein-Rathlou, N.H., Weeke, B. J. Allergy Clin. Immunol. (1987) [Pubmed]
  13. Outcome of pregnancy in women requiring corticosteroids for severe asthma. Fitzsimons, R., Greenberger, P.A., Patterson, R. J. Allergy Clin. Immunol. (1986) [Pubmed]
  14. Aqueous beclomethasone dipropionate in the treatment of ragweed pollen-induced rhinitis: further exploration of "as needed" use. Juniper, E.F., Guyatt, G.H., Archer, B., Ferrie, P.J. J. Allergy Clin. Immunol. (1993) [Pubmed]
  15. A practical guide to the management of distal ulcerative colitis. Ardizzone, S., Porro, G.B. Drugs (1998) [Pubmed]
  16. Inhaled corticosteroids reduce bone mineral density in early postmenopausal but not premenopausal asthmatic women. Fujita, K., Kasayama, S., Hashimoto, J., Nagasaka, Y., Nakano, N., Morimoto, Y., Barnes, P.J., Miyatake, A. J. Bone Miner. Res. (2001) [Pubmed]
  17. Fluticasone propionate does not influence bone metabolism in contrast to beclomethasone dipropionate. Bootsma, G.P., Dekhuijzen, P.N., Festen, J., Mulder, P.G., Swinkels, L.M., van Herwaarden, C.L. Am. J. Respir. Crit. Care Med. (1996) [Pubmed]
  18. Effects of withdrawal of inhaled steroids in men with severe irreversible airflow obstruction. O'Brien, A., Russo-Magno, P., Karki, A., Hiranniramol, S., Hardin, M., Kaszuba, M., Sherman, C., Rounds, S. Am. J. Respir. Crit. Care Med. (2001) [Pubmed]
  19. Role of microvascular permeability on physiologic differences in asthma and eosinophilic bronchitis. Kanazawa, H., Nomura, S., Yoshikawa, J. Am. J. Respir. Crit. Care Med. (2004) [Pubmed]
  20. Role of endogenous nitric oxide in exercise-induced airway narrowing in patients with bronchial asthma. Kanazawa, H., Hirata, K., Yoshikawa, J. J. Allergy Clin. Immunol. (2000) [Pubmed]
  21. Intranasal beclomethasone inhibits antigen-induced nasal hyperresponsiveness to histamine. Baroody, F.M., Cruz, A.A., Lichtenstein, L.M., Kagey-Sobotka, A., Proud, D., Naclerio, R.M. J. Allergy Clin. Immunol. (1992) [Pubmed]
  22. Inhaled corticosteroids decrease subepithelial collagen deposition by modulation of the balance between matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 expression in asthma. Hoshino, M., Takahashi, M., Takai, Y., Sim, J. J. Allergy Clin. Immunol. (1999) [Pubmed]
  23. Effect of inhaled beclomethasone dipropionate on expression of proinflammatory cytokines and activated eosinophils in the bronchial epithelium of patients with mild asthma. Wang, J.H., Trigg, C.J., Devalia, J.L., Jordan, S., Davies, R.J. J. Allergy Clin. Immunol. (1994) [Pubmed]
  24. Inhaled beclomethasone dipropionate downregulates CD4 and CD8 T-lymphocyte activation in peripheral blood of patients with asthma. Majori, M., Piccoli, M.L., Bertacco, S., Cuomo, A., Cantini, L., Pesci, A. J. Allergy Clin. Immunol. (1997) [Pubmed]
  25. Enhancement of in vitro spontaneous IgE production by topical steroids in patients with atopic dermatitis. Hiratsuka, S., Yoshida, A., Ishioka, C., Kimata, H. J. Allergy Clin. Immunol. (1996) [Pubmed]
  26. Long-term effects of beclomethasone dipropionate on prednisone dosage in the corticosteroid-dependent asthmatic. Bacal, E., Patterson, R. J. Allergy Clin. Immunol. (1978) [Pubmed]
  27. Increased vasoconstrictor sensitivity to glucocorticoids in essential hypertension. Walker, B.R., Best, R., Shackleton, C.H., Padfield, P.L., Edwards, C.R. Hypertension (1996) [Pubmed]
  28. Aerosol beclomethasone dipropionate spray compared with theophylline as primary treatment for chronic mild-to-moderate asthma. The American Academy of Allergy, Asthma and Immunology Beclomethasone Dipropionate-Theophylline Study Group. Reed, C.E., Offord, K.P., Nelson, H.S., Li, J.T., Tinkelman, D.G. J. Allergy Clin. Immunol. (1998) [Pubmed]
  29. Effect of beclomethasone dipropionate on basic fibroblast growth factor levels in induced sputum samples from asthmatic patients. Kanazawa, H., Yoshikawa, J. Ann. Allergy Asthma Immunol. (2005) [Pubmed]
  30. Relationship between vascular endothelial growth factor and angiopoietin-2 in asthmatics before and after inhaled beclomethasone therapy. Nomura, S., Kanazawa, H., Hirata, K., Iwao, H., Yoshikawa, J. The Journal of asthma : official journal of the Association for the Care of Asthma. (2005) [Pubmed]
  31. Inhalant corticosteroids inhibit hyperosmolarity-induced, and cooling and rewarming-induced interleukin-8 and RANTES production by human bronchial epithelial cells. Hashimoto, S., Gon, Y., Matsumoto, K., Takeshita, I., Maruoka, S., Horie, T. Am. J. Respir. Crit. Care Med. (2000) [Pubmed]
  32. Oropharyngeal candidiasis in patients treated with beclomethasone dipropionate delivered by metered-dose inhaler alone and with Aerochamber. Salzman, G.A., Pyszczynski, D.R. J. Allergy Clin. Immunol. (1988) [Pubmed]
  33. Safety and efficacy of fluticasone and beclomethasone in moderate to severe asthma. Belgian Multicenter Study Group. Pauwels, R.A., Yernault, J.C., Demedts, M.G., Geusens, P. Am. J. Respir. Crit. Care Med. (1998) [Pubmed]
  34. A comparison of budesonide and beclomethasone dipropionate nasal aerosols in ragweed-induced rhinitis. Vanzieleghem, M.A., Juniper, E.F. J. Allergy Clin. Immunol. (1987) [Pubmed]
  35. Effect of an inhaled corticosteroid on methacholine airway reactivity. Easton, J.G. J. Allergy Clin. Immunol. (1981) [Pubmed]
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