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Spfaer, J.A.

A dental approach to carrier screening in X linked hypohidrotic ectodermal dysplasia.

The frequency of carriers of X linked hypohidrotic ectodermal dysplasia among females with hypodontia of the permanent dentition (excluding third molars) could be as high as 1 in 500, and among females with deciduous hypodontia could be as high as 1 in 50. Since it may be possible to identify carriers form among female hypodontia cases in general by virtue of a reduced sweat pore count, the potential exists for a reasonably practical method of screening for carriers at the population level.[1]

References

A dental approach to carrier screening in X linked hypohidrotic ectodermal dysplasia. Spfaer, J.A. J. Med. Genet. (1981) [Pubmed]

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