Mebendazole therapy of parenteral trichinellosis.
Mebendazole was highly effective against the helminth parasite Trichinella spiralis in mice subjected to a 3-day course of treatment during the invasive and encystment phases of experimental trichinellosis. When treatment began either 2 or 4 weeks after the mice were inoculated with parasites, the number of larvae developing in the host musculature was greatly reduced by twice-daily oral administration of 3.125, 6.25, or 12.5 milligrams of mebendazole per kilogram of body weight.[1]References
- Mebendazole therapy of parenteral trichinellosis. McCracken, R.O., Taylor, D.D. Science (1980) [Pubmed]
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