Effect of administration of serum thymic factor ( FTS) in calves and rabbits infected with bovine immunodeficiency-like virus.
The effect of serum thymic factor ( FTS) administration in bovine immunodeficiency-like virus (BIV)-infected calves and rabbits was examined. We previously found that some of the macrophage functions were depressed and humoral immune responses against foreign proteins were delayed in BIV-infected calves compared to uninfected calves. After FTS administration, however, no delay of antibody responses against foreign proteins was observed in BIV-infected calves. Though the chemiluminescence (CL) responses of macrophages in BIV-infected calves were significantly depressed (p < 0.05), FTS administration resulted in the recovery of the CL responses in the BIV-infected calves comparable to those in the control calves. Antibody responses against foreign proteins in BIV-infected rabbits were significantly depressed (p < 0.025) as compared with those in uninfected rabbits, though the depression became no significant after FTS administration.[1]References
- Effect of administration of serum thymic factor (FTS) in calves and rabbits infected with bovine immunodeficiency-like virus. Hirai, N., Furuyama, H., Awaya, A., Onuma, M. J. Vet. Med. Sci. (1995) [Pubmed]
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