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Raizada, R.B. et al.

Dermal toxicity of hexachlorocyclohexane and pirimiphos-methyl in female rats.

Technical hexachlorocyclohexane (100 mg/kg/d) and pirimiphosmethyl EC 50 (250 mg/kg/d) given individually and in combination to female rats for 7, 15 or 30 d by skin application caused poisoning, pathomorphological changes in vital organs, and significant enzymatic changes in liver and serum. The changes produced by the 2 compounds in combination did not suggest potentiation at the tested dose levels.[1]

References

Dermal toxicity of hexachlorocyclohexane and pirimiphos-methyl in female rats. Raizada, R.B., Srivastava, M.K., Kaushal, R.A., Singh, R.P., Gupta, K.P., Dikshith, T.S. Veterinary and human toxicology. (1994) [Pubmed]

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