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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Cytochrome b-558 alpha-subunit cloning and expression in rat aortic smooth muscle cells.

Recent studies have shown that the NADPH oxidase participates in the generation of superoxide anion in non-phagocytic cells. Here we report the isolation and nucleotide sequence of a cDNA for the cytochrome b-558 alpha-subunit of the NADPH oxidase in rat vascular smooth muscle cells (VSMCs). The coding region of the cDNA was 93% homologous to mouse and 81% to human in nucleotide sequence and 96% homologous to mouse and 89% to human in the deduced amino acid sequence. Our results provide a tool with which to explore the mechanism of superoxide anion generation in rat VSMCs and other non-phagocytic cells.[1]

References

  1. Cytochrome b-558 alpha-subunit cloning and expression in rat aortic smooth muscle cells. Fukui, T., Lassègue, B., Kai, H., Alexander, R.W., Griendling, K.K. Biochim. Biophys. Acta (1995) [Pubmed]
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