The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 
 
 

Studies on the preparation of bioactive lignans by oxidative coupling reaction. V. Oxidative coupling reaction of methyl (E)-3-(2-hydroxyphenyl)propenoate derivatives and lipid peroxidation inhibitory effects of the produced lignans.

The oxidative coupling reactions of 2-hydroxycinnamates were investigated as a continuation of our previous studies on 4-hydroxy derivatives. The reaction of 2-hydroxycinnamate 1 and 2-hydroxy-4-methoxycinnamate 3 with silver oxide afforded polymerized lignin-like products, while that of 2-hydroxy-bis(methoxymethoxy)cinnamates 5 and 6, after acetylation, gave the enol acetates, 8 and 14, of oxotetrahydrobenzoxanthene derivatives, respectively. These two products were also obtained by the oxidation of 5 and 6 with potassium hexacyanoferrate(III). In the reactions of 5 and 6 with iron(III) chloride, the major products were the partially demethoxymethoxylated compounds 9 and 15, respectively. Thus, the course of the reactions in the oxidation of 2-hydroxycinnamates is quite different from that in the case of 4-hydroxy derivatives. The product 8 and the corresponding oxotetrahydrobenzoxanthene derivative were found to show moderate inhibitory effects upon lipid peroxidation.[1]

References

  1. Studies on the preparation of bioactive lignans by oxidative coupling reaction. V. Oxidative coupling reaction of methyl (E)-3-(2-hydroxyphenyl)propenoate derivatives and lipid peroxidation inhibitory effects of the produced lignans. Maeda, S., Masuda, H., Tokoroyama, T. Chem. Pharm. Bull. (1995) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities