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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Oleylamine and stearylamine increase phosphatidylserine synthesis in T cells by synergy with calcium ions.

Oleylamine and stearylamine, two cationic amphiphilic drugs, strongly increase phosphatidylserine synthesis in human T cells. The two compounds had little effect on either phosphatidylcholine or phosphatidylethanolamine synthesis. A decrease in the formation of phosphatidylethanolamine through decarboxylation of phosphatidylserine was observed, but this effect is only marginally involved in increased phosphatidylserine synthesis. The high incorporation of [3H]-serine into phosphatidylserine is a protein kinase C independent process and is due to a synergy of either oleyamine or stearylamine with calcium ions.[1]

References

  1. Oleylamine and stearylamine increase phosphatidylserine synthesis in T cells by synergy with calcium ions. Aussel, C., Pelassy, C., Bernard, A. Int. J. Biochem. Cell Biol. (1995) [Pubmed]
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