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Chemical Compound Review

Armofilm     octadecan-1-amine

Synonyms: Stearamine, Stearylamine, Oktadecylamin, OCTADECYLAMINE, Octadecanamine, ...
 
 
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Disease relevance of Noram SH

 

High impact information on Noram SH

 

Chemical compound and disease context of Noram SH

 

Biological context of Noram SH

  • In liposomes with a limiting density of SA, we found increased CRP binding with changes in composition that would increase membrane fluidity [12].
  • We have demonstrated that cationic liposomes composed of stearylamine (SA-liposomes) induce apoptosis in a variety of cells, but the mechanism responsible for the cellular death is not clear [13].
  • Cell viability was reduced after inclusion of either of the two cationic components of stearylamine and PEI [14].
  • Among the charged compounds, stearylamine was the most inhibitory and showed complete inhibition of cell growth at 100 microM [15].
  • This is accomplished by electrostatic entrapment of ZrF6(2-) ions within thermally evaporated octadecylamine (ODA) thin films followed by the low-temperature in situ hydrolysis of the entrapped metal ion complexes [16].
 

Anatomical context of Noram SH

 

Associations of Noram SH with other chemical compounds

 

Gene context of Noram SH

  • The presence of the positively charged lipid stearylamine increased the rate of association of CETP with the lipid surface [26].
  • Introduction of stearylamine in membranes containing phosphatidyl-beta-lactate (PLac) causes considerable inhibition of their prothrombin-converting activity [27].
  • Combination therapy using sodium antimony gluconate in stearylamine-bearing liposomes against established and chronic Leishmania donovani infection in BALB/c Mice [28].
  • Average size and zeta potential of SLNs of different lipids with stearylamine ranged from 96.7+/-3.8 to 163.3+/-0.7 nm and 21.3+/-1.3 to 33.2+/-0.6 mV, respectively [29].
  • To clarify the mechanism of apoptosis of the macrophage-like cell line RAW264.7 induced by cationic liposomes, we focused on the mitochondria and investigated the changes in mitochondrial membrane potential and the release of cytochrome c following treatment of cationic liposomes composed of stearylamine (SA-liposomes) [30].
 

Analytical, diagnostic and therapeutic context of Noram SH

References

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