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Duda, E.E. et al.

Computed tomography in adrenoleukodystrophy. Correlation of radiological and histological findings.

Computed tomograms (CT) demonstrated symmetrical low-density lesions in the white matter of the posterior portion of the cerebral hemispheres in a 9-year-old boy with adrenoleukodystrophy (Schilder's disease). Biopsy of the brain in an area that appeared normal on the CT scan showed profound loss of myelinated fibers and oligodendroglia; the white matter had been replaced by a rather loose acellular stroma consisting of astroglial cells and blood vessels.[1]

References

Computed tomography in adrenoleukodystrophy. Correlation of radiological and histological findings. Duda, E.E., Huttenlocher, P.R. Radiology. (1976) [Pubmed]

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