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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Sterol composition in polyene antibiotic-sensitive and resistant strains of Malassezia pachydermatis.

The membrane sterol compositions of ten strains of Malassezia pachydermatis were analysed by gas-liquid chromatography. Six of these were wild-type strains from clinical sources that were sensitive to polyene antibiotics, whereas the other four strains were resistant mutants that had arisen after treatment with N-methyl-N'-nitrosoguanidine or UV radiation. The wild-type strains contained 838.8 to 1291.7 micrograms of sterol per gram of freeze-dried mycelium. The sterols were composed of 79% ergosterol, 19% fecosterol and 2% lichesterol. The mutant strains contained 277.1 to 348.8 micrograms/g of sterols composed of 76% ergosterol and 24% fecosterol.[1]

References

  1. Sterol composition in polyene antibiotic-sensitive and resistant strains of Malassezia pachydermatis. Uchida, Y., Onodera, S., Nakade, T., Otomo, K. Vet. Res. Commun. (1994) [Pubmed]
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