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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Cloning and sequence of a chicken alpha-N-acetylgalactosaminidase gene.

A cDNA clone encoding the mature polypeptide for the chicken liver alpha-N-acetylgalactosaminidase enzyme was isolated by screening a cDNA library with a synthetic sequence derived from the human alpha-N-acetylgalactosaminidase gene. The deduced amino acid sequence of the chicken liver clone was identical to the amino-terminal and cyanogen bromide derived peptide sequences obtained from the purified enzyme. The chicken enzyme has 75% identity with the human alpha-N-acetylgalactosaminidase and 56-33% identity with alpha-galactosidases from several sources.[1]


  1. Cloning and sequence of a chicken alpha-N-acetylgalactosaminidase gene. Davis, M.O., Hata, D.J., Smith, D., Walker, J.C. Biochim. Biophys. Acta (1993) [Pubmed]
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