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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Chromosomal assignment of the gene for protein tyrosine phosphatase HPTP delta.

Protein tyrosine phosphatase ( PTP) negatively regulates the effect of protein tyrosine kinases and is implicated in the regulation of a variety of biological phenomena such as cell activation, differentiation and neoplastic transformation. To gain insight into the role of PTPs, we cloned the human receptor-type PTP gene and assigned the chromosome harboring the gene for HPTP delta by using DNAs from human-mouse hybrid cell lines and by fluorescence in situ hybridization. The results clearly demonstrated that HPTP delta gene maps to human chromosome 9p24.[1]

References

  1. Chromosomal assignment of the gene for protein tyrosine phosphatase HPTP delta. Hasegawa, K., Ariyama, T., Inazawa, J., Mizuno, K., Ogimoto, M., Katagiri, T., Yakura, H. Jpn. J. Cancer Res. (1993) [Pubmed]
 
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