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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Limited therapeutic effect of addition of buspirone in fluvoxamine-refractory obsessive-compulsive disorder.

The authors found that buspirone added to the treatment of 33 patients with obsessive-compulsive disorder who were refractory to the serotonin reuptake inhibitor fluvoxamine was no better than placebo in reducing obsessive-compulsive, depressive, or anxiety symptoms. This finding suggests that addition of buspirone to ongoing fluvoxamine therapy is not an effective treatment strategy for most patients with obsessive-compulsive disorder.[1]

References

  1. Limited therapeutic effect of addition of buspirone in fluvoxamine-refractory obsessive-compulsive disorder. McDougle, C.J., Goodman, W.K., Leckman, J.F., Holzer, J.C., Barr, L.C., McCance-Katz, E., Heninger, G.R., Price, L.H. The American journal of psychiatry. (1993) [Pubmed]
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