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MeSH Review

Obsessive-Compulsive Disorder

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Disease relevance of Obsessive-Compulsive Disorder


Psychiatry related information on Obsessive-Compulsive Disorder


High impact information on Obsessive-Compulsive Disorder


Chemical compound and disease context of Obsessive-Compulsive Disorder


Biological context of Obsessive-Compulsive Disorder


Anatomical context of Obsessive-Compulsive Disorder


Gene context of Obsessive-Compulsive Disorder


Analytical, diagnostic and therapeutic context of Obsessive-Compulsive Disorder


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  9. Specificity of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder. Comparison of fluvoxamine and desipramine. Goodman, W.K., Price, L.H., Delgado, P.L., Palumbo, J., Krystal, J.H., Nagy, L.M., Rasmussen, S.A., Heninger, G.R., Charney, D.S. Arch. Gen. Psychiatry (1990) [Pubmed]
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  11. Sertraline in children and adolescents with obsessive-compulsive disorder: a multicenter randomized controlled trial. March, J.S., Biederman, J., Wolkow, R., Safferman, A., Mardekian, J., Cook, E.H., Cutler, N.R., Dominguez, R., Ferguson, J., Muller, B., Riesenberg, R., Rosenthal, M., Sallee, F.R., Wagner, K.D., Steiner, H. JAMA (1998) [Pubmed]
  12. Differential cerebral metabolic changes with paroxetine treatment of obsessive-compulsive disorder vs major depression. Saxena, S., Brody, A.L., Ho, M.L., Alborzian, S., Maidment, K.M., Zohrabi, N., Ho, M.K., Huang, S.C., Wu, H.M., Baxter, L.R. Arch. Gen. Psychiatry (2002) [Pubmed]
  13. Multicenter double-blind comparison of sertraline and desipramine for concurrent obsessive-compulsive and major depressive disorders. Hoehn-Saric, R., Ninan, P., Black, D.W., Stahl, S., Greist, J.H., Lydiard, B., McElroy, S., Zajecka, J., Chapman, D., Clary, C., Harrison, W. Arch. Gen. Psychiatry (2000) [Pubmed]
  14. A multicenter investigation of fixed-dose fluoxetine in the treatment of obsessive-compulsive disorder. Tollefson, G.D., Rampey, A.H., Potvin, J.H., Jenike, M.A., Rush, A.J., kominguez, R.A., Koran, L.M., Shear, M.K., Goodman, W., Genduso, L.A. Arch. Gen. Psychiatry (1994) [Pubmed]
  15. Efficacy of fluvoxamine in obsessive-compulsive disorder. A double-blind comparison with placebo. Goodman, W.K., Price, L.H., Rasmussen, S.A., Delgado, P.L., Heninger, G.R., Charney, D.S. Arch. Gen. Psychiatry (1989) [Pubmed]
  16. Clomipramine treatment of obsessive-compulsive disorder. II. Biochemical aspects. Thorén, P., Asberg, M., Bertilsson, L., Mellström, B., Sjöqvist, F., Träskman, L. Arch. Gen. Psychiatry (1980) [Pubmed]
  17. Anxiety and cerebral blood flow during behavioral challenge. Dissociation of central from peripheral and subjective measures. Zohar, J., Insel, T.R., Berman, K.F., Foa, E.B., Hill, J.L., Weinberger, D.R. Arch. Gen. Psychiatry (1989) [Pubmed]
  18. A novel allele in the promoter region of the human serotonin transporter gene. Michaelovsky, E., Frisch, A., Rockah, R., Peleg, L., Magal, N., Shohat, M., Weizman, R. Mol. Psychiatry (1999) [Pubmed]
  19. Genomic organization of the SLC1A1/EAAC1 gene and mutation screening in early-onset obsessive-compulsive disorder. Veenstra-VanderWeele, J., Kim, S.J., Gonen, D., Hanna, G.L., Leventhal, B.L., Cook, E.H. Mol. Psychiatry (2001) [Pubmed]
  20. Low-level sensory processing in obsessive-compulsive disorder: an evoked potential study. Savage, C.R., Weilburg, J.B., Duffy, F.H., Baer, L., Shera, D.M., Jenike, M.A. Biol. Psychiatry (1994) [Pubmed]
  21. Neurobiology of obsessive compulsive disorder: a possible role for serotonin. Winslow, J.T., Insel, T.R. The Journal of clinical psychiatry. (1990) [Pubmed]
  22. Cerebrospinal fluid neurochemistry in children and adolescents with obsessive-compulsive disorder. Swedo, S.E., Leonard, H.L., Kruesi, M.J., Rettew, D.C., Listwak, S.J., Berrettini, W., Stipetic, M., Hamburger, S., Gold, P.W., Potter, W.Z. Arch. Gen. Psychiatry (1992) [Pubmed]
  23. Systematic changes in cerebral glucose metabolic rate after successful behavior modification treatment of obsessive-compulsive disorder. Schwartz, J.M., Stoessel, P.W., Baxter, L.R., Martin, K.M., Phelps, M.E. Arch. Gen. Psychiatry (1996) [Pubmed]
  24. Recent advances in obsessive-compulsive disorder. Rapoport, J.L. Neuropsychopharmacology (1991) [Pubmed]
  25. Amygdala volume reductions in pediatric patients with obsessive-compulsive disorder treated with paroxetine: preliminary findings. Szeszko, P.R., MacMillan, S., McMeniman, M., Lorch, E., Madden, R., Ivey, J., Banerjee, S.P., Moore, G.J., Rosenberg, D.R. Neuropsychopharmacology (2004) [Pubmed]
  26. Changes in platelet markers of obsessive-compulsive patients during a double-blind trial of fluvoxamine versus clomipramine. Marazziti, D., Pfanner, C., Palego, L., Gemignani, A., Milanfranchi, A., Ravagli, S., Lensi, P., Presta, S., Cassano, G.B. Pharmacopsychiatry (1997) [Pubmed]
  27. Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase. Prasad, H.C., Zhu, C.B., McCauley, J.L., Samuvel, D.J., Ramamoorthy, S., Shelton, R.C., Hewlett, W.A., Sutcliffe, J.S., Blakely, R.D. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  28. Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder. Hall, D., Dhilla, A., Charalambous, A., Gogos, J.A., Karayiorgou, M. Am. J. Hum. Genet. (2003) [Pubmed]
  29. Association of a glutamate (NMDA) subunit receptor gene (GRIN2B) with obsessive-compulsive disorder: a preliminary study. Arnold, P.D., Rosenberg, D.R., Mundo, E., Tharmalingam, S., Kennedy, J.L., Richter, M.A. Psychopharmacology (Berl.) (2004) [Pubmed]
  30. Pentagastrin has panic-inducing properties in obsessive compulsive disorder. de Leeuw, A.S., Den Boer, J.A., Slaap, B.R., Westenberg, H.G. Psychopharmacology (Berl.) (1996) [Pubmed]
  31. Local cerebral glucose metabolic rates in obsessive-compulsive disorder. A comparison with rates in unipolar depression and in normal controls. Baxter, L.R., Phelps, M.E., Mazziotta, J.C., Guze, B.H., Schwartz, J.M., Selin, C.E. Arch. Gen. Psychiatry (1987) [Pubmed]
  32. Cerebral glucose metabolism in childhood-onset obsessive-compulsive disorder. Revisualization during pharmacotherapy. Swedo, S.E., Pietrini, P., Leonard, H.L., Schapiro, M.B., Rettew, D.C., Goldberger, E.L., Rapoport, S.I., Rapoport, J.L., Grady, C.L. Arch. Gen. Psychiatry (1992) [Pubmed]
  33. Regional xenon 133 cerebral blood flow and cerebral technetium 99m HMPAO uptake in unmedicated patients with obsessive-compulsive disorder and matched normal control subjects. Determination by high-resolution single-photon emission computed tomography. Rubin, R.T., Villanueva-Meyer, J., Ananth, J., Trajmar, P.G., Mena, I. Arch. Gen. Psychiatry (1992) [Pubmed]
  34. Controlled comparisons of clomipramine and fluoxetine in the treatment of obsessive-compulsive disorder. Behavioral and biological results. Pigott, T.A., Pato, M.T., Bernstein, S.E., Grover, G.N., Hill, J.L., Tolliver, T.J., Murphy, D.L. Arch. Gen. Psychiatry (1990) [Pubmed]
  35. Prolactin and cortisol responses to MK-212, a serotonin agonist, in obsessive-compulsive disorder. Bastani, B., Nash, J.F., Meltzer, H.Y. Arch. Gen. Psychiatry (1990) [Pubmed]
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