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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

A high-resolution genetic map of mouse chromosome 15 encompassing the Dominant megacolon (Dom) locus.

Dominant megacolon (Dom) is one of four mutations in the mouse that can produce a phenotype similar to Hirschsprung disease in human. The Dom gene product is not known, and no candidate region has been defined for a possible human homolog. In this publication we report mapping the Dom locus with high definition, using several intra-and interspecific crosses and a set of 16 Chr 15-specific microsatellites flanking this locus.[1]

References

  1. A high-resolution genetic map of mouse chromosome 15 encompassing the Dominant megacolon (Dom) locus. Puliti, A., Prehu, M.O., Simon-Chazottes, D., Ferkdadji, L., Peuchmaur, M., Goossens, M., Guénet, J.L. Mamm. Genome (1995) [Pubmed]
 
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