Gene Review:
Sox10 - SRY (sex determining region Y)-box 10
Mus musculus
Synonyms:
Dom, Protein SOX-21, Sox-10, Sox21, Transcription factor SOX-10, ...
- Genetic evidence does not support direct regulation of EDNRB by SOX10 in migratory neural crest and the melanocyte lineage. Hakami, R.M., Hou, L., Baxter, L.L., Loftus, S.K., Southard-Smith, E.M., Incao, A., Cheng, J., Pavan, W.J. Mech. Dev. (2006)
- Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect. Maka, M., Stolt, C.C., Wegner, M. Dev. Biol. (2005)
- SOX10 mutations in patients with Waardenburg-Hirschsprung disease. Pingault, V., Bondurand, N., Kuhlbrodt, K., Goerich, D.E., Préhu, M.O., Puliti, A., Herbarth, B., Hermans-Borgmeyer, I., Legius, E., Matthijs, G., Amiel, J., Lyonnet, S., Ceccherini, I., Romeo, G., Smith, J.C., Read, A.P., Wegner, M., Goossens, M. Nat. Genet. (1998)
- Expression of connexin47 in oligodendrocytes is regulated by the Sox10 transcription factor. Schlierf, B., Werner, T., Glaser, G., Wegner, M. J. Mol. Biol. (2006)
- Direct regulation of the Microphthalmia promoter by Sox10 links Waardenburg-Shah syndrome (WS4)-associated hypopigmentation and deafness to WS2. Lee, M., Goodall, J., Verastegui, C., Ballotti, R., Goding, C.R. J. Biol. Chem. (2000)
- Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model. Southard-Smith, E.M., Kos, L., Pavan, W.J. Nat. Genet. (1998)
- The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Stolt, C.C., Lommes, P., Sock, E., Chaboissier, M.C., Schedl, A., Wegner, M. Genes Dev. (2003)
- Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Stolt, C.C., Rehberg, S., Ader, M., Lommes, P., Riethmacher, D., Schachner, M., Bartsch, U., Wegner, M. Genes Dev. (2002)
- Sox10 regulates ciliary neurotrophic factor gene expression in Schwann cells. Ito, Y., Wiese, S., Funk, N., Chittka, A., Rossoll, W., Bömmel, H., Watabe, K., Wegner, M., Sendtner, M. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Melanocyte-specific expression of dopachrome tautomerase is dependent on synergistic gene activation by the Sox10 and Mitf transcription factors. Ludwig, A., Rehberg, S., Wegner, M. FEBS Lett. (2004)
- Direct interaction of Sox10 with the promoter of murine Dopachrome Tautomerase (Dct) and synergistic activation of Dct expression with Mitf. Jiao, Z., Mollaaghababa, R., Pavan, W.J., Antonellis, A., Green, E.D., Hornyak, T.J. Pigment Cell Res. (2004)
- Interspecies difference in the regulation of melanocyte development by SOX10 and MITF. Hou, L., Arnheiter, H., Pavan, W.J. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Deletion of long-range sequences at Sox10 compromises developmental expression in a mouse model of Waardenburg-Shah (WS4) syndrome. Antonellis, A., Bennett, W.R., Menheniott, T.R., Prasad, A.B., Lee-Lin, S.Q., Green, E.D., Paisley, D., Kelsh, R.N., Pavan, W.J., Ward, A. Hum. Mol. Genet. (2006)
- Interactions between Sox10, Edn3 and Ednrb during enteric nervous system and melanocyte development. Stanchina, L., Baral, V., Robert, F., Pingault, V., Lemort, N., Pachnis, V., Goossens, M., Bondurand, N. Dev. Biol. (2006)
- Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord. Stolt, C.C., Schmitt, S., Lommes, P., Sock, E., Wegner, M. Dev. Biol. (2005)
- Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor Sox8. Sock, E., Schmidt, K., Hermanns-Borgmeyer, I., Bösl, M.R., Wegner, M. Mol. Cell. Biol. (2001)
- Activation of myelin genes during transdifferentiation from melanoma to glial cell phenotype. Slutsky, S.G., Kamaraju, A.K., Levy, A.M., Chebath, J., Revel, M. J. Biol. Chem. (2003)
- Sumoylation modulates transcriptional activity of MITF in a promoter-specific manner. Murakami, H., Arnheiter, H. Pigment Cell Res. (2005)
- Synergistic transcriptional activation by Sox10 and Sp1 family members. Melnikova, I.N., Lin, H.R., Blanchette, A.R., Gardner, P.D. Neuropharmacology (2000)
- Olig bHLH proteins interact with homeodomain proteins to regulate cell fate acquisition in progenitors of the ventral neural tube. Sun, T., Echelard, Y., Lu, R., Yuk, D.I., Kaing, S., Stiles, C.D., Rowitch, D.H. Curr. Biol. (2001)
- Sox10 is required for the early development of the prospective neural crest in Xenopus embryos. Honoré, S.M., Aybar, M.J., Mayor, R. Dev. Biol. (2003)
- Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine. Young, H.M., Bergner, A.J., Müller, T. J. Comp. Neurol. (2003)
- X-ray-induced deletion complexes in embryonic stem cells on mouse chromosome 15. Chick, W.S., Mentzer, S.E., Carpenter, D.A., Rinchik, E.M., Johnson, D., You, Y. Mamm. Genome (2005)
- Checkpoints of melanocyte stem cell development. Sommer, L. Sci. STKE (2005)
- Cooperative function of POU proteins and SOX proteins in glial cells. Kuhlbrodt, K., Herbarth, B., Sock, E., Enderich, J., Hermans-Borgmeyer, I., Wegner, M. J. Biol. Chem. (1998)
- The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10. Mou, Z., Tapper, A.R., Gardner, P.D. J. Biol. Chem. (2009)
- Sox10-rtTA mouse line for tetracycline-inducible expression of transgenes in neural crest cells and oligodendrocytes. Ludwig, A., Schlierf, B., Schardt, A., Nave, K.A., Wegner, M. Genesis (2004)
- Expression of the Sox10 gene during mouse inner ear development. Watanabe, K., Takeda, K., Katori, Y., Ikeda, K., Oshima, T., Yasumoto, K., Saito, H., Takasaka, T., Shibahara, S. Brain Res. Mol. Brain Res. (2000)
- Neuronal defects in genotyped dominant megacolon (Dom) mouse embryos, a model for Hirschsprung disease. Puliti, A., Poirier, V., Goossens, M., Simonneau, M. Neuroreport (1996)