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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Microsatellite Repeats

 
 
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Disease relevance of Microsatellite Repeats

 

Psychiatry related information on Microsatellite Repeats

 

High impact information on Microsatellite Repeats

 

Chemical compound and disease context of Microsatellite Repeats

 

Biological context of Microsatellite Repeats

 

Anatomical context of Microsatellite Repeats

 

Associations of Microsatellite Repeats with chemical compounds

  • We present microsatellite DNA evidence for the hypothesis that Cabernet Sauvignon is the progeny of two other Bordeaux cultivars, Cabernet franc and Sauvignon blanc [31].
  • Based on a linkage analysis of 11 families segregating for this syndrome using microsatellite repeat polymorphisms throughout the human genome, we found the Wolfram syndrome gene to be linked to markers on the short arm of human chromosome 4, with Zmax = 6.46 at theta = 0.02 for marker D4S431 [32].
  • Here we show that microsatellite genetic markers can be used to assign individual cod from three different populations in the northeastern Atlantic Ocean to their population of origin [33].
  • 363 nondiabetic Pima Indians were genotyped at 516 polymorphic microsatellite markers on all 22 autosomes [34].
  • Cox proportional hazard modeling was used to determine survival associations for microsatellite instability and 5-fluorouracil treatment status [35].
 

Gene context of Microsatellite Repeats

  • In yeast, mutations in several genes, including RTH and MSH3, cause microsatellite instability [36].
  • Mice that are deficient in either the Pms2 or Msh2 DNA mismatch repair genes have microsatellite instability and a predisposition to tumours [37].
  • Cells in culture stably expressing a dominant-negative MLH3 protein exhibit microsatellite instability [38].
  • Here mice deficient in another mismatch repair gene, Mlh1, possess not only microsatellite instability but are also infertile (both males and females) [37].
  • In four H-JEB kindreds, a maximum two-point lod score of 5.33 at theta = 0 was observed between a microsatellite near LAMC2 at 1q25-31 and the disease [39].
 

Analytical, diagnostic and therapeutic context of Microsatellite Repeats

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