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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Development of an integrated radiotherapy network system.

PURPOSE: To introduce the process of developing an integrated radiotherapy network. METHODS AND MATERIALS: We developed a new radiotherapy treatment-planning system in 1987 that we named the Computer Tomography (CT) simulator. CT images were immediately transported to multiimage monitors and to a planning computer, and treatment planning could be performed with the patient lying on the CT couch. The results of planning were used to guide a laser projector, and radiation fields were projected onto the skin of the patient. Since 1991, an integrated radiotherapy network system has been developed, which consists of a picture archiving and communicating system (PACS), a radiotherapy information database, a CT simulator, and a linear accelerator with a multileaf collimator. RESULTS: Clinical experience has been accumulated in more than 1,000 patients. Based on our 7 years of experience, we have modified several components of our original CT simulator and have developed a second generation CT simulator. A standard protocol has been developed for communication between the CT scanner, treatment planning computer, and radiotherapy apparatus using the Ethernet network. As a result, treatment planning data can be transported to the linear accelerator within 1 min after completion of treatment planning. CONCLUSION: This system enables us to make optimal use of CT information and to devise accurate three-dimensional (3D) treatment-planning programs. Our network also allows for the performance of fully computer-controlled dynamic arc conformal therapy.[1]


  1. Development of an integrated radiotherapy network system. Nagata, Y., Okajima, K., Murata, R., Mitsumori, M., Mizowaki, T., Yamamoto, M., Hiraoka, M., Nishidai, T., Nakata, M., Abe, M., Sugahara, K., Arimura, H., Hosoba, M., Morisawa, H., Kazusa, C., Ai, D., Kokubo, M. Int. J. Radiat. Oncol. Biol. Phys. (1996) [Pubmed]
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