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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Therapeutic effects of CDP-choline in Alzheimer's disease. Cognition, brain mapping, cerebrovascular hemodynamics, and immune factors.

CDP-choline was given to patients with Alzheimer's disease (AD) at a daily dose of 1000 mg/day p.o. for one month. This compound slightly improved mental performance, tended to reduce theta activity in fronto-temporal regions, increasing alpha power in occipital areas, and enhanced cerebrovascular perfusion by increasing blood flow velocity and reducing pulsatility and resistance indexes. In addition, CDP-choline diminished histamine and interleukin-1 levels in blood and serum, respectively, and increased plasma TNF.[1]

References

  1. Therapeutic effects of CDP-choline in Alzheimer's disease. Cognition, brain mapping, cerebrovascular hemodynamics, and immune factors. Cacabelos, R., Caamaño, J., Gómez, M.J., Fernández-Novoa, L., Franco-Maside, A., Alvarez, X.A. Ann. N. Y. Acad. Sci. (1996) [Pubmed]
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