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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q.

Metabotropic glutamate receptors (GRMs) are neurotransmitter receptors that respond to glutamate stimulations by activating GTP-binding proteins and modulating second-messenger cascades. Eight related GRMs have been identified to date. In this study, we have mapped GRM3 and GRM8 to human chromosome 7q21.1-q21.2 and 7q31.3-q32.1, respectively, using somatic cell hybrid and fluorescence in situ hybridization analysis. A yeast artificial chromosome contig was constructed surrounding the genes, allowing their location to be integrated into the genetic and physical map of chromosome 7.[1]

References

  1. Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q. Scherer, S.W., Duvoisin, R.M., Kuhn, R., Heng, H.H., Belloni, E., Tsui, L.C. Genomics (1996) [Pubmed]
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