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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Evidence for cholecystokininA receptors in bovine adrenal chromaffin cells.

We have studied a possible role of cholecystokinin ( CCK) in regulating adrenal medullary function. Caerulein (10(-10)-10(-7) M), a CCK receptor agonist, increased formation of inositol phosphates in primary cultured bovine adrenal medullary (BAM) chromaffin cells in a concentration-dependent manner. The effect of caerulein was antagonized by devazepide, a selective CCKA-receptor antagonist, but not by L-365.260, a selective CCKB-receptor antagonist. These results suggest that BAM cells possess functional CCK receptors of the CCKA-subtype. Stimulation of these receptors with caerulein activates a signal transduction pathway via phospholipase C. CCK may regulate catecholamine release in BAM cells.[1]

References

  1. Evidence for cholecystokininA receptors in bovine adrenal chromaffin cells. Aarnisalo, A.M., Vainio, P.J., Männistö, P.T., Vasar, E., Tuominen, R.K. Neuroreport (1996) [Pubmed]
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