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Hou, X.S. et al.

Hou, Perrimon,

The JAK-STAT pathway in Drosophila.

Recent studies in Drosophila have identified a single JAK and a single STAT protein. Genetic and biochemical analyses reveal that these two proteins operate in the same signal transduction pathway. Phenotypic analyses of JAK and STAT mutants implicate this pathway in a number of developmental decisions, in particular the regulation of pair-rule genes and fly hematopoiesis.[1]

References

The JAK-STAT pathway in Drosophila. Hou, X.S., Perrimon, N. Trends Genet. (1997) [Pubmed]

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