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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Self-stimulation of the subfornical organ and lateral hypothalamus: differential effects of atropine and methysergide.

The effects of cholinergic blockade of neurons by atropine or serotonergic blockade by methysergide was investigated in rats responding for brain-stimulation reward. Bipolar stimulating electrodes were placed either in the subfornical organ (SFO) or the lateral hypothalamus (LH). Atropine sulphate and methysergide significantly suppressed self-stimulation of the SFO but not of the LH, suggesting that cholinergic and serotonergic neurons are involved in brain-stimulation reward associated with this site.[1]

References

  1. Self-stimulation of the subfornical organ and lateral hypothalamus: differential effects of atropine and methysergide. Robertson, A., Kucharczyk, J., Mogenson, G.J. Pharmacol. Biochem. Behav. (1977) [Pubmed]
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