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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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In vitro plasmid-encoded resistance to quinolones.

The possibility of plasmid-encoded quinolone resistance is explored in two model systems. In the first, increasing amounts of wild-type gyrA allele moderately increased minimum inhibitory concentrations to quinolone antibiotics. In the second model, a mutant gyrA allele encoded by a multicopy plasmid produced a quinolone resistance phenotype upon its expression in a quinolone-susceptible Escherichia coli strain.[1]

References

  1. In vitro plasmid-encoded resistance to quinolones. Gómez-Gómez, J.M., Blázquez, J., Espinosa De Los Monteros, L.E., Baquero, M.R., Baquero, F., Martínez, J.L. FEMS Microbiol. Lett. (1997) [Pubmed]
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