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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Changes in auxin response from mutations in an AUX/IAA gene.

Transcription of the AUX/IAA family of genes is rapidly induced by the plant hormone auxin, but evidence that AUX/IAA genes mediate further responses to auxin has been elusive. Changes in diverse auxin responses result from mutations in the Arabidopsis AXR3 gene. AXR3 was shown to be a member of the AUX/IAA family, providing direct evidence that AUX/IAA genes are central in auxin signaling. Molecular characterization of axr3 gain-of- function and loss-of- function mutations established the functional importance of domains conserved among AUX/IAA proteins.[1]

References

  1. Changes in auxin response from mutations in an AUX/IAA gene. Rouse, D., Mackay, P., Stirnberg, P., Estelle, M., Leyser, O. Science (1998) [Pubmed]
 
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