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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

The usefulness of screening for chlamydial trachomatis infection with cervical mucus leukocyte esterase.

OBJECTIVE: To evaluate the ability of leukocyte esterase dipstick test (LET) performed in cervical mucus to predict direct immunofluorescent (DIF)-verified Chlamydia trachomatis (Ct) cervical infection. METHOD: Eighty women with inflammatory cervico-vaginal smear were submitted to both an endocervical smear, to verify Ct cervicitis by DIF technique; and a cervical mucus sample to perform LET. Results of LET and DIF were matched. RESULTS: Among 30 Chlamydial positive subjects, cervical mucus esterase test was positive in 28 (93.3%); while among 50 Chlamydial negative controls, esterase test was negative in 43 subject (86%). The sensitivity, specificity, positive and negative predictive values for LET were 93.3%, 86%, 80% and 95% respectively. CONCLUSION: Cervical mucus LET is a simple, cost effective screening test, with promising accuracy, for Ct cervical infection among women with inflammatory cervico-vaginal smears.[1]

References

  1. The usefulness of screening for chlamydial trachomatis infection with cervical mucus leukocyte esterase. el-Shourbagy, M., Diab, K.M., Abdalla, M.Y., el-Salam, M.A., Mohasb, S.H. J. Obstet. Gynaecol. Res. (1998) [Pubmed]
 
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