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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Pigmented Bowen's disease.

We describe two Afro-Caribbean women who presented with pigmented Bowen's disease. One, a 44-year-old woman, developed a sharply demarcated, irregularly marginated, hyperpigmented plaque with a velvety surface in the perianal area. The other, a 25-year-old woman, developed a well defined, verrucous, hyperpigmented patch on the umbilicus. Histology showed that both cases were Bowen's disease, and subsequent treatment with 5-fluorouracil and cryotherapy led to complete resolution.[1]


  1. Pigmented Bowen's disease. Papageorgiou, P.P., Koumarianou, A.A., Chu, A.C. Br. J. Dermatol. (1998) [Pubmed]
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