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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
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Disease relevance of Histology


Psychiatry related information on Histology


High impact information on Histology

  • We studied 102 postmenopausal women undergoing estrogen therapy who also took a progestin for 12 days each month, and we correlated the day of onset of bleeding with the endometrial histology over a three-month period [11].
  • Administration of iodine during the first 10 weeks of life increased the incidence of the disease, as determined by histology and the measurement of autoantibodies to triiodothyronine, thyroxine, and thyroglobulin [12].
  • In contrast, RCAS-c-myc induced endocrine tumors exclusively, as determined by histology and detection of differentiation markers [13].
  • Quantitative histology of thin, nondecalcified sections was performed on sequential bone biopsy specimens from five patients undergoing long-term hemodialysis and treated with calcifediol (25-hydroxycholecalciferol) for periods of three to nine months [14].
  • Adult MMP9-deficient (MMP9(-/)-) mice showed normal renal histology and function at 3 mo [15].

Chemical compound and disease context of Histology


Biological context of Histology


Anatomical context of Histology


Associations of Histology with chemical compounds


Gene context of Histology


Analytical, diagnostic and therapeutic context of Histology


  1. Mutant glycosyltransferase and altered glycosylation of alpha-dystroglycan in the myodystrophy mouse. Grewal, P.K., Holzfeind, P.J., Bittner, R.E., Hewitt, J.E. Nat. Genet. (2001) [Pubmed]
  2. Multidrug resistance in breast cancer: a meta-analysis of MDR1/gp170 expression and its possible functional significance. Trock, B.J., Leonessa, F., Clarke, R. J. Natl. Cancer Inst. (1997) [Pubmed]
  3. Pulmonary response of fifth component of complement-sufficient and -deficient mice to hyperoxia. Parrish, D.A., Mitchell, B.C., Henson, P.M., Larsen, G.L. J. Clin. Invest. (1984) [Pubmed]
  4. Nephroblastoma in the rat: histology of a spontaneous tumor, identity with respect to renal mesenchymal neoplasms, and a review of previously recorded cases. Hard, G.C., Grasso, P. J. Natl. Cancer Inst. (1976) [Pubmed]
  5. Identification of subsets of neuroblastomas by combined histopathologic and N-myc analysis. Shimada, H., Stram, D.O., Chatten, J., Joshi, V.V., Hachitanda, Y., Brodeur, G.M., Lukens, J.N., Matthay, K.K., Seeger, R.C. J. Natl. Cancer Inst. (1995) [Pubmed]
  6. Protein profiling in cardiac tissue in response to the chronic effects of alcohol. Patel, V.B., Corbett, J.M., Dunn, M.J., Winrow, V.R., Portmann, B., Richardson, P.J., Preedy, V.R. Electrophoresis (1997) [Pubmed]
  7. Apolipoprotein E epsilon4 allele has no effect on age at onset or duration of disease in cases of frontotemporal dementia with pick- or microvacuolar-type histology. Pickering-Brown, S.M., Owen, F., Isaacs, A., Snowden, J., Varma, A., Neary, D., Furlong, R., Daniel, S.E., Cairns, N.J., Mann, D.M. Exp. Neurol. (2000) [Pubmed]
  8. Histopathological changes underlying frontotemporal lobar degeneration with clinicopathological correlation. Shi, J., Shaw, C.L., Du Plessis, D., Richardson, A.M., Bailey, K.L., Julien, C., Stopford, C., Thompson, J., Varma, A., Craufurd, D., Tian, J., Pickering-Brown, S., Neary, D., Snowden, J.S., Mann, D.M. Acta Neuropathol. (2005) [Pubmed]
  9. Choice (CRT) and simple reaction times (SRT) compared in laboratory technicians: factors influencing reaction times and a predictive model. Miller, J.A., Cohen, G.S., Warshaw, R., Thornton, J.C., Kilburn, K.H. Am. J. Ind. Med. (1989) [Pubmed]
  10. Fetal membrane histology in preterm premature rupture of membranes: comparison to controls, and between antibiotic and placebo treatment. The National Institute of Child Health and Human Development Maternal Fetal Medicine Units Network, Bethesda, MD, USA. Bendon, R.W., Faye-Petersen, O., Pavlova, Z., Qureshi, F., Mercer, B., Miodovnik, M., Das, A.F., Meis, P.J., Moawad, A.H., Iams, J.D., McNellis, D. Pediatr. Dev. Pathol. (1999) [Pubmed]
  11. A simple method for determining the optimal dosage of progestin in postmenopausal women receiving estrogens. Padwick, M.L., Pryse-Davies, J., Whitehead, M.I. N. Engl. J. Med. (1986) [Pubmed]
  12. Induction of autoimmune thyroiditis in chickens by dietary iodine. Bagchi, N., Brown, T.R., Urdanivia, E., Sundick, R.S. Science (1985) [Pubmed]
  13. The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer. Lewis, B.C., Klimstra, D.S., Varmus, H.E. Genes Dev. (2003) [Pubmed]
  14. Calcifediol in chronic renal insufficiency. Skeletal response. Teitelbaum, S.L., Bone, J.M., Stein, P.M., Gilden, J.J., Bates, M., Boisseau, V.C., Avioli, L.V. JAMA (1976) [Pubmed]
  15. Matrix metalloproteinase 9 protects mice from anti-glomerular basement membrane nephritis through its fibrinolytic activity. Lelongt, B., Bengatta, S., Delauche, M., Lund, L.R., Werb, Z., Ronco, P.M. J. Exp. Med. (2001) [Pubmed]
  16. Effect of a chemically defined diet in liquid form on colon carcinogenesis in rats. Tatsuta, M., Yamamura, H., Iishi, H., Ichii, M., Noguchi, S., Baba, M., Taniguchi, H. J. Natl. Cancer Inst. (1985) [Pubmed]
  17. Reversibility of extensive liver damage in galactosemia. Applebaum, M.N., Thaler, M.M. Gastroenterology (1975) [Pubmed]
  18. Treatment of osteoporosis of ageing with 1alpha-hydroxycholecalciferol. Lund, B., Hjorth, L., Kjaer, I., Reimann, I., Friis, T., Andersen, R.B., Sorensen, O.H. Lancet (1975) [Pubmed]
  19. Ursodeoxycholic acid treatment of bile reflux gastritis. Stefaniwsky, A.B., Tint, G.S., Speck, J., Shefer, S., Salen, G. Gastroenterology (1985) [Pubmed]
  20. Indomethacin produces gastric antral ulcers in the refed rat. Satoh, H., Inada, I., Hirata, T., Maki, Y. Gastroenterology (1981) [Pubmed]
  21. RNA expression of the WT1 gene in Wilms' tumors in relation to histology. Miwa, H., Tomlinson, G.E., Timmons, C.F., Huff, V., Cohn, S.L., Strong, L.C., Saunders, G.F. J. Natl. Cancer Inst. (1992) [Pubmed]
  22. Assessment of hormone dependence of comedo ductal carcinoma in situ of the breast. Holland, P.A., Knox, W.F., Potten, C.S., Howell, A., Anderson, E., Baildam, A.D., Bundred, N.J. J. Natl. Cancer Inst. (1997) [Pubmed]
  23. Integrated state of subgenomic fragments of hepatitis B virus DNA in hepatocellular carcinoma from mainland China. Zhou, Y.Z., Butel, J.S., Li, P.J., Finegold, M.J., Melnick, J.L. J. Natl. Cancer Inst. (1987) [Pubmed]
  24. Ploidy as a prognostic determinant in surgically treated lung cancer. Zimmerman, P.V., Hawson, G.A., Bint, M.H., Parsons, P.G. Lancet (1987) [Pubmed]
  25. Mutations in the p53 gene: an early marker of neoplastic progression in ulcerative colitis. Brentnall, T.A., Crispin, D.A., Rabinovitch, P.S., Haggitt, R.C., Rubin, C.E., Stevens, A.C., Burmer, G.C. Gastroenterology (1994) [Pubmed]
  26. Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury. Kelly, K.J., Williams, W.W., Colvin, R.B., Meehan, S.M., Springer, T.A., Gutierrez-Ramos, J.C., Bonventre, J.V. J. Clin. Invest. (1996) [Pubmed]
  27. Inhibitory effects of tetragastrin and histamine on carcinogenesis in the small intestines of W rats by N-methyl-N'-nitro-N-nitrosoguanidine. Tatsuta, M., Iishi, H., Ichii, M., Noguchi, S., Yamamura, H., Taniguchi, H. J. Natl. Cancer Inst. (1986) [Pubmed]
  28. Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. Zhang, X., Schwarz, E.M., Young, D.A., Puzas, J.E., Rosier, R.N., O'Keefe, R.J. J. Clin. Invest. (2002) [Pubmed]
  29. Effect of prostaglandins E2 and I2 and of indomethacin on deoxycholic acid-induced damage to the rat bile-pancreatic duct. Olazábal, A. Gastroenterology (1983) [Pubmed]
  30. Celiac disease-like abnormalities in a subgroup of patients with irritable bowel syndrome. Wahnschaffe, U., Ullrich, R., Riecken, E.O., Schulzke, J.D. Gastroenterology (2001) [Pubmed]
  31. Degradation of endogenous bacterial cell wall polymers by the muralytic enzyme mutanolysin prevents hepatobiliary injury in genetically susceptible rats with experimental intestinal bacterial overgrowth. Lichtman, S.N., Okoruwa, E.E., Keku, J., Schwab, J.H., Sartor, R.B. J. Clin. Invest. (1992) [Pubmed]
  32. Stat-3 is required for pulmonary homeostasis during hyperoxia. Hokuto, I., Ikegami, M., Yoshida, M., Takeda, K., Akira, S., Perl, A.K., Hull, W.M., Wert, S.E., Whitsett, J.A. J. Clin. Invest. (2004) [Pubmed]
  33. Cationic Yersinia antigen-induced chronic allergic arthritis in rats. A model for reactive arthritis in humans. Mertz, A.K., Batsford, S.R., Curschellas, E., Kist, M.J., Gondolf, K.B. J. Clin. Invest. (1991) [Pubmed]
  34. Experimental liver cirrhosis induced by alcohol and iron. Tsukamoto, H., Horne, W., Kamimura, S., Niemelä, O., Parkkila, S., Ylä-Herttuala, S., Brittenham, G.M. J. Clin. Invest. (1995) [Pubmed]
  35. Griseofulvin-induced cholestasis in Swiss albino mice. Yokoo, H., Craig, R.M., Harwood, T.R., Cochrane, C. Gastroenterology (1979) [Pubmed]
  36. Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure. Melnikov, V.Y., Ecder, T., Fantuzzi, G., Siegmund, B., Lucia, M.S., Dinarello, C.A., Schrier, R.W., Edelstein, C.L. J. Clin. Invest. (2001) [Pubmed]
  37. Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity. Liu, Z.X., Govindarajan, S., Kaplowitz, N. Gastroenterology (2004) [Pubmed]
  38. Loss of Klf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach. Katz, J.P., Perreault, N., Goldstein, B.G., Actman, L., McNally, S.R., Silberg, D.G., Furth, E.E., Kaestner, K.H. Gastroenterology (2005) [Pubmed]
  39. Mouse mammary tumor virus c-rel transgenic mice develop mammary tumors. Romieu-Mourez, R., Kim, D.W., Shin, S.M., Demicco, E.G., Landesman-Bollag, E., Seldin, D.C., Cardiff, R.D., Sonenshein, G.E. Mol. Cell. Biol. (2003) [Pubmed]
  40. Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9. Yang, Y., Kuang, Y., De Oca, R.M., Hays, T., Moreau, L., Lu, N., Seed, B., D'Andrea, A.D. Blood (2001) [Pubmed]
  41. Two enteropathogenic Escherichia coli type III secreted proteins, EspA and EspB, are virulence factors. Abe, A., Heczko, U., Hegele, R.G., Brett Finlay, B. J. Exp. Med. (1998) [Pubmed]
  42. The role of antibodies in acute vascular rejection of pig-to-baboon cardiac transplants. Lin, S.S., Weidner, B.C., Byrne, G.W., Diamond, L.E., Lawson, J.H., Hoopes, C.W., Daniels, L.J., Daggett, C.W., Parker, W., Harland, R.C., Davis, R.D., Bollinger, R.R., Logan, J.S., Platt, J.L. J. Clin. Invest. (1998) [Pubmed]
  43. IP-10-induced recruitment of CXCR3 host T cells is required for small bowel allograft rejection. Zhang, Z., Kaptanoglu, L., Tang, Y., Ivancic, D., Rao, S.M., Luster, A., Barrett, T.A., Fryer, J. Gastroenterology (2004) [Pubmed]
  44. Protective effect of sucralfate against alcohol-induced gastric mucosal injury in the rat. Macroscopic, histologic, ultrastructural, and functional time sequence analysis. Hollander, D., Tarnawski, A., Krause, W.J., Gergely, H. Gastroenterology (1985) [Pubmed]
  45. Esophageal ulceration activates keratinocyte growth factor and its receptor in rats: implications for ulcer healing. Baatar, D., Kawanaka, H., Szabo, I.L., Pai, R., Jones, M.K., Kitano, S., Tarnawski, A.S. Gastroenterology (2002) [Pubmed]
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