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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

CO2-induced panic attacks: a twin study.

OBJECTIVE: The authors investigated the role of genetic factors in 35% CO2-induced panic attacks. METHOD: Ninety twins recruited from the general population were challenged with one-vital-capacity inhalations of 35% CO2-65% O2. Probandwise concordance rates were calculated and rates compared for monozygotic and for dizygotic twins. RESULTS: A significantly higher concordance was found for 35% CO2-induced panic attacks among monozygotic than dizygotic twins (55.6% versus 12.5%). CONCLUSIONS: These results suggest a relevant role of genetic factors in 35% CO2-induced panic attacks.[1]


  1. CO2-induced panic attacks: a twin study. Bellodi, L., Perna, G., Caldirola, D., Arancio, C., Bertani, A., Di Bella, D. The American journal of psychiatry. (1998) [Pubmed]
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