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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Focal grey matter heterotopias in monozygotic twins with developmental language disorder.

We describe 9-year-old monozygotic male twins with a developmental language disorder of the phonologic-syntactic type and learning difficulties. High-resolution MRI revealed bilateral parieto-temporal grey matter heterotopias in both twins, on the left more than on the right, and more pronounced in the more affected twin. This suggests a causal relationship between the heterotopias and the neuropsychological findings in this twin pair. CONCLUSION: Neuronal migration defects and ensuing focal heterotopias may be causally related to developmental language disorders.[1]

References

  1. Focal grey matter heterotopias in monozygotic twins with developmental language disorder. Preis, S., Engelbrecht, V., Huang, Y., Steinmetz, H. Eur. J. Pediatr. (1998) [Pubmed]
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