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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

An adolescent male with multiple paraphilias successfully treated with fluoxetine.

Little is known about the psychiatric diagnosis and treatment of adolescents who sexually offend. We therefore describe an adolescent sex offender who met DSM-IV criteria for multiple paraphilias (except for the age criterion), bipolar type II disorder, and OCD, whose paraphilic urges and behaviors, depression, and violent obsessions responded to open label fluoxetine after failing to respond to long-term residential treatment. Although only a single and uncontrolled observation, this case suggests that some adolescent sex offenders may in fact have paraphilias, and that paraphilias in adolescents, like those in adults, may respond to serotonin reuptake inhibitors.[1]


  1. An adolescent male with multiple paraphilias successfully treated with fluoxetine. Galli, V.B., Raute, N.J., McConville, B.J., McElroy, S.L. Journal of child and adolescent psychopharmacology. (1998) [Pubmed]
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