Chemical Compound Review:
Fluoxetin N-methyl-3-phenyl-3-[4...
Synonyms:
Pulvules, Reneuron, Floxetine, Fluoxeren, Foxetin, ...
Mitchell,
Kroenke,
Stella,
Mailliard,
Perez,
Loprinzi,
L??nnqvist,
Swindle,
Sloan,
Klaukka,
Kelly,
Stang,
Novotny,
Halyard,
Quella,
Haukka,
Kaufman,
Hiemke,
Pruthi,
Rummans,
Härtter,
Kero,
Zhou,
Tiihonen,
West,
Dolor,
Laine,
Rosenberg,
Wahlbeck,
Gilsenan,
Weinberger,
Hays,
Tanskanen,
Anderson,
Eckert,
Ekblad,
Heikkinen,
- Fluoxetine. Gram, L. N. Engl. J. Med. (1994)
- Birth outcomes in pregnant women taking fluoxetine. Chambers, C.D., Johnson, K.A., Dick, L.M., Felix, R.J., Jones, K.L. N. Engl. J. Med. (1996)
- Effects of desipramine, amitriptyline, and fluoxetine on pain in diabetic neuropathy. Max, M.B., Lynch, S.A., Muir, J., Shoaf, S.E., Smoller, B., Dubner, R. N. Engl. J. Med. (1992)
- Fluoxetine and fibromyalgia. Finestone, D.H., Ober, S.K. JAMA (1990)
- Pregnancy outcome following first-trimester exposure to fluoxetine (Prozac). Pastuszak, A., Schick-Boschetto, B., Zuber, C., Feldkamp, M., Pinelli, M., Sihn, S., Donnenfeld, A., McCormack, M., Leen-Mitchell, M., Woodland, C. JAMA (1993)
- Neurodevelopment of children exposed in utero to antidepressant drugs. Nulman, I., Rovet, J., Stewart, D.E., Wolpin, J., Gardner, H.A., Theis, J.G., Kulin, N., Koren, G. N. Engl. J. Med. (1997)
- Randomised, double-blind, placebo-controlled study of fluoxetine in chronic fatigue syndrome. Vercoulen, J.H., Swanink, C.M., Zitman, F.G., Vreden, S.G., Hoofs, M.P., Fennis, J.F., Galama, J.M., van der Meer, J.W., Bleijenberg, G. Lancet (1996)
- A multicenter investigation of fixed-dose fluoxetine in the treatment of obsessive-compulsive disorder. Tollefson, G.D., Rampey, A.H., Potvin, J.H., Jenike, M.A., Rush, A.J., kominguez, R.A., Koran, L.M., Shear, M.K., Goodman, W., Genduso, L.A. Arch. Gen. Psychiatry (1994)
- Clinical improvement with fluoxetine therapy and noradrenergic function in patients with panic disorder. Coplan, J.D., Papp, L.A., Pine, D., Martinez, J., Cooper, T., Rosenblum, L.A., Klein, D.F., Gorman, J.M. Arch. Gen. Psychiatry (1997)
- Fluoxetine in the treatment of premenstrual dysphoria. Canadian Fluoxetine/Premenstrual Dysphoria Collaborative Study Group. Steiner, M., Steinberg, S., Stewart, D., Carter, D., Berger, C., Reid, R., Grover, D., Streiner, D. N. Engl. J. Med. (1995)
- Cloning and expression of a functional serotonin transporter from rat brain. Blakely, R.D., Berson, H.E., Fremeau, R.T., Caron, M.G., Peek, M.M., Prince, H.K., Bradley, C.C. Nature (1991)
- High-affinity uptake of serotonin into immunocytochemically identified astrocytes. Kimelberg, H.K., Katz, D.M. Science (1985)
- MPTP-induced duodenal ulcers in rat. Prevention by reuptake blockers for serotonin and norepinephrine, but not dopamine. Keshavarzian, A., Wibowo, A., Gordon, J.H., Fields, J.Z. Gastroenterology (1990)
- The portal pressure response to beta-blockade is greater in cirrhotic patients without varices than in those with varices. Escorsell, A., Ferayorni, L., Bosch, J., García-Pagán, J.C., García-Tsao, G., Grace, N.D., Rodés, J., Groszmann, R.J. Gastroenterology (1997)
- Effects of exposure to selective serotonin reuptake inhibitors during pregnancy on serotonergic symptoms in newborns and cord blood monoamine and prolactin concentrations. Laine, K., Heikkinen, T., Ekblad, U., Kero, P. Arch. Gen. Psychiatry (2003)
- Propranolol in the prevention of the first hemorrhage from esophagogastric varices: A multicenter, randomized clinical trial. The Boston-New Haven-Barcelona Portal Hypertension Study Group. Conn, H.O., Grace, N.D., Bosch, J., Groszmann, R.J., Rodés, J., Wright, S.C., Matloff, D.S., Garcia-Tsao, G., Fisher, R.L., Navasa, M. Hepatology (1991)
- Phase III evaluation of fluoxetine for treatment of hot flashes. Loprinzi, C.L., Sloan, J.A., Perez, E.A., Quella, S.K., Stella, P.J., Mailliard, J.A., Halyard, M.Y., Pruthi, S., Novotny, P.J., Rummans, T.A. J. Clin. Oncol. (2002)
- Fenfluramine and fluoxetine spare protein consumption while suppressing caloric intake by rats. Wurtman, J.J., Wurtman, R.J. Science (1977)
- Portal hypertension enhances endotoxin-induced intercellular adhesion molecule 1 up-regulation in the rat. Panés, J., Perry, M.A., Anderson, D.C., Muzykantov, V.R., Carden, D.L., Miyasaka, M., Granger, D.N. Gastroenterology (1996)
- Distorted microangioarchitecture and impaired angiogenesis in gastric mucosa of portal hypertensive rats. Ichikawa, Y., Tarnawski, A., Sarfeh, I.J., Ishikawa, T., Shimada, H. Gastroenterology (1994)
- Modulation of ionic currents in isolated canine and human jejunal circular smooth muscle cells by fluoxetine. Farrugia, G. Gastroenterology (1996)
- Overexpressed nitric oxide synthase in portal-hypertensive stomach of rat: a key to increased susceptibility to damage? Ohta, M., Tanoue, K., Tarnawski, A.S., Pai, R., Itani, R.M., Sander, F.C., Sugimachi, K., Sarfeh, I.J. Gastroenterology (1997)
- Portal hypertension activates the nitric oxide synthase genes in the esophageal mucosa of rats. Tanoue, K., Ohta, M., Tarnawski, A.S., Wahlstrom, K.J., Sugimachi, K., Sarfeh, I.J. Gastroenterology (1996)
- Similar effectiveness of paroxetine, fluoxetine, and sertraline in primary care: a randomized trial. Kroenke, K., West, S.L., Swindle, R., Gilsenan, A., Eckert, G.J., Dolor, R., Stang, P., Zhou, X.H., Hays, R., Weinberger, M. JAMA (2001)
- Antidepressants and the risk of suicide, attempted suicide, and overall mortality in a nationwide cohort. Tiihonen, J., L??nnqvist, J., Wahlbeck, K., Klaukka, T., Tanskanen, A., Haukka, J. Arch. Gen. Psychiatry (2006)
- Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine. Uzunova, V., Sheline, Y., Davis, J.M., Rasmusson, A., Uzunov, D.P., Costa, E., Guidotti, A. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac). Svenningsson, P., Tzavara, E.T., Witkin, J.M., Fienberg, A.A., Nomikos, G.G., Greengard, P. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Chronic fluoxetine treatment increases the expression of PSA-NCAM in the medial prefrontal cortex. Varea, E., Blasco-Ibáñez, J.M., Gómez-Climent, M.A., Castillo-Gómez, E., Crespo, C., Martínez-Guijarro, F.J., Nácher, J. Neuropsychopharmacology (2007)
- Overlapping and distinct brain regions associated with the anxiolytic effects of chlordiazepoxide and chronic fluoxetine. Bechtholt, A.J., Valentino, R.J., Lucki, I. Neuropsychopharmacology (2008)
- Fluoxetine inhibits multidrug resistance extrusion pumps and enhances responses to chemotherapy in syngeneic and in human xenograft mouse tumor models. Peer, D., Dekel, Y., Melikhov, D., Margalit, R. Cancer Res. (2004)
- Investigation of serotonin-related genes in antidepressant response. Peters, E.J., Slager, S.L., McGrath, P.J., Knowles, J.A., Hamilton, S.P. Mol. Psychiatry (2004)
- Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans. Licinio, J., O'Kirwan, F., Irizarry, K., Merriman, B., Thakur, S., Jepson, R., Lake, S., Tantisira, K.G., Weiss, S.T., Wong, M.L. Mol. Psychiatry (2004)
- Pharmacokinetics of selective serotonin reuptake inhibitors. Hiemke, C., Härtter, S. Pharmacol. Ther. (2000)
- Prediction of In Vivo Drug-Drug Interactions from In Vitro Data : Factors Affecting Prototypic Drug-Drug Interactions Involving CYP2C9, CYP2D6 and CYP3A4. Brown, H.S., Galetin, A., Hallifax, D., Houston, J.B. Clinical pharmacokinetics. (2006)
- Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey. Kaufman, D.W., Kelly, J.P., Rosenberg, L., Anderson, T.E., Mitchell, A.A. JAMA (2002)