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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Linkage of proximal myotonic myopathy to chromosome 3q.

We performed genetic linkage analysis in nine German proximal myotonic myopathy (PROMM) families using DNA-markers D3S1541 and D3S1589 from the region of the recently discovered gene locus of myotonic dystrophy type 2 (DM2) on chromosome 3q. Two-point analysis supplied an lod score of 5. 9. We conclude that a gene causing PROMM is located on chromosome 3q. PROMM and DM2 may be allelic disorders or may be caused by closely linked genes.[1]

References

  1. Linkage of proximal myotonic myopathy to chromosome 3q. Ricker, K., Grimm, T., Koch, M.C., Schneider, C., Kress, W., Reimers, C.D., Schulte-Mattler, W., Mueller-Myhsok, B., Toyka, K.V., Mueller, C.R. Neurology (1999) [Pubmed]
 
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