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Hpn  -  hepsin

Mus musculus

Synonyms: AA408042, AI788568, Hlb320, Serine protease hepsin
 
 
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Disease relevance of Hpn

 

High impact information on Hpn

 

Biological context of Hpn

 

Anatomical context of Hpn

 

Associations of Hpn with chemical compounds

 

Other interactions of Hpn

 

Analytical, diagnostic and therapeutic context of Hpn

References

  1. Mouse matriptase-2: identification, characterization and comparative mRNA expression analysis with mouse hepsin in adult and embryonic tissues. Hooper, J.D., Campagnolo, L., Goodarzi, G., Truong, T.N., Stuhlmann, H., Quigley, J.P. Biochem. J. (2003) [Pubmed]
  2. Hepsin promotes prostate cancer progression and metastasis. Klezovitch, O., Chevillet, J., Mirosevich, J., Roberts, R.L., Matusik, R.J., Vasioukhin, V. Cancer Cell (2004) [Pubmed]
  3. Generation and characterization of mice deficient in hepsin, a hepatic transmembrane serine protease. Wu, Q., Yu, D., Post, J., Halks-Miller, M., Sadler, J.E., Morser, J. J. Clin. Invest. (1998) [Pubmed]
  4. Identification and cloning of the membrane-associated serine protease, hepsin, from mouse preimplantation embryos. Vu, T.K., Liu, R.W., Haaksma, C.J., Tomasek, J.J., Howard, E.W. J. Biol. Chem. (1997) [Pubmed]
  5. Complete nucleotide sequence, origin of isoform and functional characterization of the mouse hepsin gene. Kawamura, S., Kurachi, S., Deyashiki, Y., Kurachi, K. Eur. J. Biochem. (1999) [Pubmed]
  6. HEPSIN inhibits cell growth/invasion in prostate cancer cells. Srikantan, V., Valladares, M., Rhim, J.S., Moul, J.W., Srivastava, S. Cancer Res. (2002) [Pubmed]
  7. Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture. Xuan, J.A., Schneider, D., Toy, P., Lin, R., Newton, A., Zhu, Y., Finster, S., Vogel, D., Mintzer, B., Dinter, H., Light, D., Parry, R., Polokoff, M., Whitlow, M., Wu, Q., Parry, G. Cancer Res. (2006) [Pubmed]
  8. Pro-urokinase-type Plasminogen Activator Is a Substrate for Hepsin. Moran, P., Li, W., Fan, B., Vij, R., Eigenbrot, C., Kirchhofer, D. J. Biol. Chem. (2006) [Pubmed]
  9. Cloning, genomic organization, chromosomal assignment and expression of a novel mosaic serine proteinase: epitheliasin. Jacquinet, E., Rao, N.V., Rao, G.V., Hoidal, J.R. FEBS Lett. (2000) [Pubmed]
  10. Mice deficient in hepsin, a serine protease, exhibit normal embryogenesis and unchanged hepatocyte regeneration ability. Yu, I.S., Chen, H.J., Lee, Y.S., Huang, P.H., Lin, S.R., Tsai, T.W., Lin, S.W. Thromb. Haemost. (2000) [Pubmed]
  11. Embryotrophic factor-3 from human oviductal cells enhances proliferation, suppresses apoptosis and stimulates the expression of the beta1 subunit of sodium-potassium ATPase in mouse embryos. Xu, J.S., Lee, Y.L., Lee, K.F., Kwok, K.L., Lee, W.M., Luk, J.M., Yeung, W.S. Hum. Reprod. (2004) [Pubmed]
  12. Gene targeting in hemostasis. Hepsin. Wu, Q. Front. Biosci. (2001) [Pubmed]
 
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