Gene Review:
SSTR3 - somatostatin receptor 3
Homo sapiens
Synonyms:
SS-3-R, SS3-R, SS3R, SSR-28, Somatostatin receptor type 3
- Somatostatin receptor subtype gene expression in pituitary adenomas. Miller, G.M., Alexander, J.M., Bikkal, H.A., Katznelson, L., Zervas, N.T., Klibanski, A. J. Clin. Endocrinol. Metab. (1995)
- Somatostatin receptors in pituitary and development of somatostatin receptor subtype-selective analogs. Shimon, I. Endocrine (2003)
- Somatostatin and somatostatin receptors in the diagnosis and treatment of gliomas. Lamszus, K., Meyerhof, W., Westphal, M. J. Neurooncol. (1997)
- Expression of somatostatin receptors in normal and cirrhotic human liver and in hepatocellular carcinoma. Reynaert, H., Rombouts, K., Vandermonde, A., Urbain, D., Kumar, U., Bioulac-Sage, P., Pinzani, M., Rosenbaum, J., Geerts, A. Gut (2004)
- Expression of somatostatin receptor (SSTR) subtypes in pituitary adenomas: quantitative analysis of SSTR2 mRNA by reverse transcription-polymerase chain reaction. Murabe, H., Shimatsu, A., Ihara, C., Mizuta, H., Nakamura, Y., Nagata, I., Kikuchi, H., Nakao, K. J. Neuroendocrinol. (1996)
- Somatostatin and its receptor family. Patel, Y.C. Frontiers in neuroendocrinology. (1999)
- Somatostatin receptor subtype specificity and in vivo binding of a novel tumor tracer, 99mTc-P829. Virgolini, I., Leimer, M., Handmaker, H., Lastoria, S., Bischof, C., Muto, P., Pangerl, T., Gludovacz, D., Peck-Radosavljevic, M., Lister-James, J., Hamilton, G., Kaserer, K., Valent, P., Dean, R. Cancer Res. (1998)
- Expression and localization of somatostatin receptor SSTR1, SSTR2, and SSTR3 messenger RNAs in primary human tumors using in situ hybridization. Reubi, J.C., Schaer, J.C., Waser, B., Mengod, G. Cancer Res. (1994)
- Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis. Kumar, U., Sasi, R., Suresh, S., Patel, A., Thangaraju, M., Metrakos, P., Patel, S.C., Patel, Y.C. Diabetes (1999)
- The effect of somatostatin and SSTR3 on proliferation and apoptosis of gastric cancer cells. Hu, C., Yi, C., Hao, Z., Cao, S., Li, H., Shao, X., Zhang, J., Qiao, T., Fan, D. Cancer Biol. Ther. (2004)
- G protein coupled receptor signaled apoptosis is associated with activation of a cation insensitive acidic endonuclease and intracellular acidification. Sharma, K., Srikant, C.B. Biochem. Biophys. Res. Commun. (1998)
- Subtype-selective induction of wild-type p53 and apoptosis, but not cell cycle arrest, by human somatostatin receptor 3. Sharma, K., Patel, Y.C., Srikant, C.B. Mol. Endocrinol. (1996)
- Point mutation of the somatostatin receptor 2 gene in the human small cell lung cancer cell line COR-L103. Zhang, C.Y., Yokogoshi, Y., Yoshimoto, K., Fujinaka, Y., Matsumoto, K., Saito, S. Biochem. Biophys. Res. Commun. (1995)
- A novel system that reports the G-proteins linked to a given receptor: a study of type 3 somatostatin receptor. Komatsuzaki, K., Murayama, Y., Giambarella, U., Ogata, E., Seino, S., Nishimoto, I. FEBS Lett. (1997)
- Somatostatin receptor (SSTR) expression and function in normal and leukaemic T-cells. Evidence for selective effects on adhesion to extracellular matrix components via SSTR2 and/or 3. Talme, T., Ivanoff, J., Hägglund, M., Van Neerven, R.J., Ivanoff, A., Sundqvist, K.G. Clin. Exp. Immunol. (2001)
- Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase. Yamada, Y., Reisine, T., Law, S.F., Ihara, Y., Kubota, A., Kagimoto, S., Seino, M., Seino, Y., Bell, G.I., Seino, S. Mol. Endocrinol. (1992)
- Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain. Kaupmann, K., Bruns, C., Hoyer, D., Seuwen, K., Lübbert, H. FEBS Lett. (1993)
- Phosphorylation of four amino acid residues in the carboxyl terminus of the rat somatostatin receptor subtype 3 is crucial for its desensitization and internalization. Roth, A., Kreienkamp, H.J., Meyerhof, W., Richter, D. J. Biol. Chem. (1997)
- Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation. Law, S.F., Zaina, S., Sweet, R., Yasuda, K., Bell, G.I., Stadel, J., Reisine, T. Mol. Pharmacol. (1994)
- Expression of IGFBP-3 by human retinal endothelial cell cultures: IGFBP-3 involvement in growth inhibition and apoptosis. Spoerri, P.E., Caballero, S., Wilson, S.H., Shaw, L.C., Grant, M.B. Invest. Ophthalmol. Vis. Sci. (2003)
- Expression of somatostatin receptor subtypes (SSTR1-5) in Alzheimer's disease brain: an immunohistochemical analysis. Kumar, U. Neuroscience (2005)
- Somatostatin receptor subtype expression in human thyroid and thyroid carcinoma cell lines. Ain, K.B., Taylor, K.D., Tofiq, S., Venkataraman, G. J. Clin. Endocrinol. Metab. (1997)
- Pituitary cell line GH3 expresses two somatostatin receptor subtypes that inhibit adenylyl cyclase: functional expression of rat somatostatin receptor subtypes 1 and 2 in human embryonic kidney 293 cells. Garcia, P.D., Myers, R.M. Mol. Pharmacol. (1994)
- Further delineation of the continuous human neoplastic enterochromaffin cell line, KRJ-I, and the inhibitory effects of lanreotide and rapamycin. Kidd, M., Eick, G.N., Modlin, I.M., Pfragner, R., Champaneria, M.C., Murren, J. J. Mol. Endocrinol. (2007)