Gene Review:
TCL1A - T-cell leukemia/lymphoma 1A
Homo sapiens
Synonyms:
Oncogene TCL-1, Oncogene TCL1, Protein p14 TCL1, T-cell leukemia/lymphoma protein 1A, TCL1
- The role of TCL1 in human T-cell leukemia. Pekarsky, Y., Hallas, C., Croce, C.M. Oncogene (2001)
- Differential expression of TCL1 during pre-B-cell acute lymphoblastic leukemia progression. Fears, S., Chakrabarti, S.R., Nucifora, G., Rowley, J.D. Cancer Genet. Cytogenet. (2002)
- Chromosomal and genetic aberrations differ with meningioma subtype. Wada, K., Maruno, M., Suzuki, T., Kagawa, N., Hashiba, T., Fujimoto, Y., Hashimoto, N., Izumoto, S., Yoshimine, T. Brain tumor pathology. (2004)
- Crystal structure of MTCP-1: implications for role of TCL-1 and MTCP-1 in T cell malignancies. Fu, Z.Q., Du Bois, G.C., Song, S.P., Kulikovskaya, I., Virgilio, L., Rothstein, J.L., Croce, C.M., Weber, I.T., Harrison, R.W. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Molecular basis of mature T-cell leukemia. Pekarsky, Y., Hallas, C., Croce, C.M. JAMA (2001)
- The protooncogene TCL1 is an Akt kinase coactivator. Laine, J., Künstle, G., Obata, T., Sha, M., Noguchi, M. Mol. Cell (2000)
- Purification and characterization of recombinant forms of murine Tcl1 proteins. Du Bois, G.C., Song, S.P., Kulikovskaya, I., Rothstein, J.L., Germann, M.W., Croce, C.M. Protein Expr. Purif. (2000)
- Molecular analysis of a t(14;14) translocation in leukemic T-cells of an ataxia telangiectasia patient. Russo, G., Isobe, M., Gatti, R., Finan, J., Batuman, O., Huebner, K., Nowell, P.C., Croce, C.M. Proc. Natl. Acad. Sci. U.S.A. (1989)
- T cell leukemia I oncogene expression depends on the presence of Epstein-Barr virus in the virus-carrying Burkitt lymphoma lines. Kiss, C., Nishikawa, J., Takada, K., Trivedi, P., Klein, G., Szekely, L. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Identification of the TCL1 gene involved in T-cell malignancies. Virgilio, L., Narducci, M.G., Isobe, M., Billips, L.G., Cooper, M.D., Croce, C.M., Russo, G. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Regulation of TCL1 expression in B- and T-cell lymphomas and reactive lymphoid tissues. Narducci, M.G., Pescarmona, E., Lazzeri, C., Signoretti, S., Lavinia, A.M., Remotti, D., Scala, E., Baroni, C.D., Stoppacciaro, A., Croce, C.M., Russo, G. Cancer Res. (2000)
- Identification of TCL1A as an immunohistochemical marker of adverse outcome in diffuse large B-cell lymphomas. Ramuz, O., Bouabdallah, R., Devilard, E., Borie, N., Groulet-Martinec, A., Bardou, V.J., Brousset, P., Bertucci, F., Birg, F., Birnbaum, D., Xerri, L. Int. J. Oncol. (2005)
- Abnormalities at 14q32.1 in T cell malignancies involve two oncogenes. Pekarsky, Y., Hallas, C., Isobe, M., Russo, G., Croce, C.M. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Identification of Nerve Growth Factor-responsive Element of the TCL1 Promoter as a Novel Negative Regulatory Element. Hiromura, M., Suizu, F., Narita, M., Kinowaki, K., Noguchi, M. J. Biol. Chem. (2006)
- A modeled hydrophobic domain on the TCL1 oncoprotein mediates association with AKT at the cytoplasmic membrane. French, S.W., Shen, R.R., Koh, P.J., Malone, C.S., Mallick, P., Teitell, M.A. Biochemistry (2002)
- Characterization of the TCL-1 transgenic mouse as a preclinical drug development tool for human chronic lymphocytic leukemia. Johnson, A.J., Lucas, D.M., Muthusamy, N., Smith, L.L., Edwards, R.B., De Lay, M.D., Croce, C.M., Grever, M.R., Byrd, J.C. Blood (2006)
- Patterned CpG methylation of silenced B cell gene promoters in classical Hodgkin lymphoma-derived and primary effusion lymphoma cell lines. Doerr, J.R., Malone, C.S., Fike, F.M., Gordon, M.S., Soghomonian, S.V., Thomas, R.K., Tao, Q., Murray, P.G., Diehl, V., Teitell, M.A., Wall, R. J. Mol. Biol. (2005)
- High TCL1 expression and intact T-cell receptor signaling define a hyperproliferative subset of T-cell prolymphocytic leukemia. Herling, M., Patel, K.A., Teitell, M.A., Konopleva, M., Ravandi, F., Kobayashi, R., Jones, D. Blood (2008)
- T-cell prolymphocytic leukaemia: antigen receptor gene rearrangement and a novel mode of MTCP1 B1 activation. De Schouwer, P.J., Dyer, M.J., Brito-Babapulle, V.B., Matutes, E., Catovsky, D., Yuille, M.R. Br. J. Haematol. (2000)
- Differential regulation of Akt kinase isoforms by the members of the TCL1 oncogene family. Laine, J., Künstle, G., Obata, T., Noguchi, M. J. Biol. Chem. (2002)
- Crystal structure of p14TCL1, an oncogene product involved in T-cell prolymphocytic leukemia, reveals a novel beta-barrel topology. Hoh, F., Yang, Y.S., Guignard, L., Padilla, A., Stern, M.H., Lhoste, J.M., van Tilbeurgh, H. Structure (1998)
- Characterization and localization of the TCL-1 oncogene product. Fu, T.B., Virgilio, L., Narducci, M.G., Facchiano, A., Russo, G., Croce, C.M. Cancer Res. (1994)
- TCL-1, MTCP-1 and TML-1 gene expression profile in non-leukemic clonal proliferations associated with ataxia-telangiectasia. Chun, H.H., Castellví-Bel, S., Wang, Z., Nagourney, R.A., Plaeger, S., Becker-Catania, S.G., Naeim, F., Sparkes, R.S., Gatti, R.A. Int. J. Cancer (2002)
- Chromosome walking on the TCL1 locus involved in T-cell neoplasia. Virgilio, L., Isobe, M., Narducci, M.G., Carotenuto, P., Camerini, B., Kurosawa, N., Abbas-ar-Rushdi, n.u.l.l., Croce, C.M., Russo, G. Proc. Natl. Acad. Sci. U.S.A. (1993)
- TCL1 oncogene activation in preleukemic T cells from a case of ataxia-telangiectasia. Narducci, M.G., Virgilio, L., Isobe, M., Stoppacciaro, A., Elli, R., Fiorilli, M., Carbonari, M., Antonelli, A., Chessa, L., Croce, C.M., Russo, G. Blood (1995)