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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 80 documents. Results 1 - 10.

Homo sapiens
Gene: ... both the binding of ACF to apoB RNA and C to U RNA editing. The APOBEC1 nuclear export signal...RNA. This complex contains apobec- 1, the catalytic subunit, and apobec- 1 complementation factor( ACF ), the RNA... to the mooring sequence in apo- B mRNA and docks apobec- 1 to deaminate its target cytidine. Apobec1 is regulated... / Synonyms: APOBEC1-stimulating protein; APOBEC1CF
Mus musculus
Gene: ... Disease relevance of Apobec1 In contrast, in apoE -/- mice, inactivation of apobec- 1 caused... elevation. Apobec- 1 protects intestine from radiation injury through posttranscriptional regulation... by overexpression of AID, Apobec- 1, and related members of the RNA- editing cytidine deaminase family suggested... / Synonyms: C->U-editing enzyme APOBEC-1
Rattus norvegicus
Gene: ... Disease relevance of Apobec1 METHODS AND RESULTS: Transcutaneous injection of recombinant adenovirus expressing Apobec1( AvApobec1) into the liver of newborn rabbits in vivo resulted in efficient Apobec1 expression until Day 50, as detected by PCR- Southern blot analysis. In comparison, over... / Synonyms: C->U-editing enzyme APOBEC-1
Homo sapiens
Gene: ... Disease relevance of APOBEC1 Three of these, rat APOBEC1, mouse APOBEC3, and human APOBEC3B, are able to inhibit HIV infectivity even in the presence of Vif. APOBEC1 is structurally homologous... the type II transcript and apobec- 1, the catalytic subunit of the apolipoprotein B mRNA- editing enzyme... / Synonyms: APOBEC-1; C->U-editing enzyme APOBEC-1
Rattus norvegicus
Gene: ... regulation of apoB mRNA editing is associated with phosphorylation of APOBEC- 1 complementation factor. Two...( APOBEC- 1) complementation factor( ACF) family of related proteins. Caspases, Asp- specific cysteine... Moreover, alkaline phosphatase treatment of nuclear extracts reduced the amount of APOBEC- 1 co... / Synonyms: APOBEC1-stimulating protein; Apobec-1
Mus musculus
Gene: ... plays a crucial role, which is independent of apobec- 1 expression, in cell survival, particularly..., which altered Asp to Ser at amino acid 363. Other interactions of 1810073H04Rik Hepatic apobec- 1 complementation factor mRNA and protein abundance were significantly decreased, whereas apobec- 1 mRNA and protein... / Synonyms: APOBEC1-stimulating protein; apobec-1 complementation factor
Monodelphis domestica
Gene: ... High impact information on APOBEC1 An APOBEC- 1- like enzyme such as might be involved in C -> U RNA editing of tRNA in marsupial mitochondria was not demonstrated. Biological context of APOBEC1 These studies extend the origins of APOBEC- 1 back 170 000 000 years to marsupials and help bridge the gap...
Homo sapiens
Gene: ... , resulting in delayed cell cycle progression. The transgene expression of the catalytic subunit APOBEC- 1...
Homo sapiens
Gene: ... differentiation. Down- regulation of ABBP- 1 in an apobec- 1- expressing HepG2 cell line by transfection with an antisense ABBP- 1 cDNA construct leads to inhibition of endogenous apoB mRNA editing. Cloning of an Apobec... We used the yeast two- hybrid system to identify an apobec- 1- interacting protein, ABBP- 1... / Synonyms: APOBEC1-binding protein 1
MeSH term: ... . Gene context of Nucleocapsid In conclusion, APOBEC3G and APOBEC3F but not rat APOBEC1 can downregulate...

 

 
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