Gene Review:
Apobec1 - apolipoprotein B mRNA editing enzyme,...
Rattus norvegicus
Synonyms:
Apolipoprotein B mRNA-editing enzyme 1, C->U-editing enzyme APOBEC-1
- Normal perinatal rise in serum cholesterol is inhibited by hepatic delivery of adenoviral vector expressing apolipoprotein B mRNA editing enzyme (Apobec1) in rabbits. Wu, Y., Teng, B.B., Brandt, M.L., Piedra, P.A., Liu, J., Chan, L. J. Surg. Res. (1999)
- Apolipoprotein B RNA sequence 3' of the mooring sequence and cellular sources of auxiliary factors determine the location and extent of promiscuous editing. Sowden, M.P., Eagleton, M.J., Smith, H.C. Nucleic Acids Res. (1998)
- Apobec-1 transcription in rat colon cancer: decreased apobec-1 protein production through alterations in polysome distribution and mRNA translation associated with upstream AUGs. Anant, S., Mukhopadhyay, D., Hirano, K., Brasitus, T.A., Davidson, N.O. Biochim. Biophys. Acta (2002)
- APOBEC-mediated editing of viral RNA. Bishop, K.N., Holmes, R.K., Sheehy, A.M., Malim, M.H. Science (2004)
- Molecular cloning of an apolipoprotein B messenger RNA editing protein. Teng, B., Burant, C.F., Davidson, N.O. Science (1993)
- An auxiliary factor containing a 240-kDa protein complex is involved in apolipoprotein B RNA editing. Schock, D., Kuo, S.R., Steinburg, M.F., Bolognino, M., Sparks, J.D., Sparks, C.E., Smith, H.C. Proc. Natl. Acad. Sci. U.S.A. (1996)
- A sequence-specific RNA-binding protein complements apobec-1 To edit apolipoprotein B mRNA. Mehta, A., Driscoll, D.M. Mol. Cell. Biol. (1998)
- Identification of novel alternative splice variants of APOBEC-1 complementation factor with different capacities to support apolipoprotein B mRNA editing. Sowden, M.P., Lehmann, D.M., Lin, X., Smith, C.O., Smith, H.C. J. Biol. Chem. (2004)
- Mutagenesis of apobec-1 complementation factor reveals distinct domains that modulate RNA binding, protein-protein interaction with apobec-1, and complementation of C to U RNA-editing activity. Blanc, V., Henderson, J.O., Kennedy, S., Davidson, N.O. J. Biol. Chem. (2001)
- Adenovirus-mediated gene transfer of rat apolipoprotein B mRNA-editing protein in mice virtually eliminates apolipoprotein B-100 and normal low density lipoprotein production. Teng, B., Blumenthal, S., Forte, T., Navaratnam, N., Scott, J., Gotto, A.M., Chan, L. J. Biol. Chem. (1994)
- Partial characterization of the auxiliary factors involved in apolipoprotein B mRNA editing through APOBEC-1 affinity chromatography. Yang, Y., Yang, Y., Kovalski, K., Smith, H.C. J. Biol. Chem. (1997)
- Inhibition of the apolipoprotein B mRNA editing enzyme-complex by hnRNP C1 protein and 40S hnRNP complexes. Greeve, J., Lellek, H., Rautenberg, P., Greten, H. Biol. Chem. (1998)
- In vitro deamination of cytosine to uracil in single-stranded DNA by apolipoprotein B editing complex catalytic subunit 1 (APOBEC1). Petersen-Mahrt, S.K., Neuberger, M.S. J. Biol. Chem. (2003)
- Induction of cytidine to uridine editing on cytoplasmic apolipoprotein B mRNA by overexpressing APOBEC-1. Yang, Y., Sowden, M.P., Smith, H.C. J. Biol. Chem. (2000)
- Metabolic regulation of apoB mRNA editing is associated with phosphorylation of APOBEC-1 complementation factor. Lehmann, D.M., Galloway, C.A., Sowden, M.P., Smith, H.C. Nucleic Acids Res. (2006)
- Hepatic gene transfer of the catalytic subunit of the apolipoprotein B mRNA editing enzyme results in a reduction of plasma LDL levels in normal and watanabe heritable hyperlipidemic rabbits. Greeve, J., Jona, V.K., Chowdhury, N.R., Horwitz, M.S., Chowdhury, J.R. J. Lipid Res. (1996)
- apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, is a novel RNA-binding protein. Anant, S., MacGinnitie, A.J., Davidson, N.O. J. Biol. Chem. (1995)
- Disproportionate relationship between APOBEC-1 expression and apolipoprotein B mRNA editing activity. Siddiqui, J.F., Van Mater, D., Sowden, M.P., Smith, H.C. Exp. Cell Res. (1999)
- Tissue-specific, developmental and nutritional regulation of the gene encoding the catalytic subunit of the rat apolipoprotein B mRNA editing enzyme: functional role in the modulation of apoB mRNA editing. Funahashi, T., Giannoni, F., DePaoli, A.M., Skarosi, S.F., Davidson, N.O. J. Lipid Res. (1995)