Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

APOBEC1 - apolipoprotein B mRNA editing enzyme,...

Monodelphis domestica

Fujino, T. et al.

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High impact information on APOBEC1

An APOBEC-1-like enzyme such as might be involved in C->U RNA editing of tRNA in marsupial mitochondria was not demonstrated [1].

Biological context of APOBEC1

These studies extend the origins of APOBEC-1 back 170 000 000 years to marsupials and help bridge the gap in the origins of this RNA editing process between birds and eutherian mammals [1].

Analytical, diagnostic and therapeutic context of APOBEC1

Northern blot and RT-PCR analyses and an editing assay indicate that no APOBEC-1 was expressed in the liver [1].

References

C-->U editing of apolipoprotein B mRNA in marsupials: identification and characterisation of APOBEC-1 from the American opossum Monodelphus domestica. Fujino, T., Navaratnam, N., Jarmuz, A., von Haeseler, A., Scott, J. Nucleic Acids Res. (1999) [Pubmed]

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