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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 93 documents. Results 1 - 10.

Homo sapiens
Gene: ... . The insulator binding protein CTCF associates with the nuclear matrix. In all cell lines analyzed, including...Disease relevance of CTCF Reciprocal binding of CTCF and BORIS to the NY- ESO- 1 promoter coincides with derepression of this cancer- testis gene in lung cancer cells. Our results identify CTCF as a novel epigenetic... / Synonyms: Transcriptional repressor CTCF
Drosophila melanogaster
Gene: ... High impact information on CTCF In addition, we demonstrate that one of the insulators( Fab- 8) in the Drosophila Abdominal- B locus mediates enhancer blocking by dCTCF. We have uncovered significant bioinformatics evidence that CTCF is widespread, at least among Drosophila species. As such, CTCF may provide... / Synonyms: dCTCF
Rattus norvegicus
Gene: ... High impact information on Ctcf In particular, over- expression of 11- zinc finger protein and glypican may be responsible for the inhibition of axonal growth and regeneration. In addition, Ctcf... with malignant growth in vivo. Biological context of Ctcf The disruption of Ctcf, which encodes a repressor... / Synonyms: Transcriptional repressor CTCF
Mus musculus
Gene: ... to loss of Igf2 imprinting. All known vertebrate chromatin insulators interact with the highly conserved...Disease relevance of Ctcf A chromatin insulator- like element in the herpes simplex virus type 1... and silencing activities. High impact information on Ctcf Four repeats in the DMD bind CCCTC- binding factor... / Synonyms: Transcriptional repressor CTCF
Gallus gallus
Gene: ... phosphorylation by substituting all serines within this site resulted in markedly enhanced repression of the CTS...Disease relevance of CTCF CTCF transgenic chicken embryos and mice were established by lipofection and microinjection of linearized cytomegalovirus( CMV )- CTCF construct into fertilized eggs and mouse oocytes...
Xenopus laevis
Gene: ... Disease relevance of ctcf The glucocorticoid receptor precludes the binding of a transcriptional... on ctcf Microinjection of wild- type or dominant- negative RARalpha rescued the morpholino phenotype... functions as a transcriptional repressor to induce mesoderm. Biological context of ctcf Barhl2 promotes...
MeSH term: ... of virtually all intracellular sodium pumps to the plasma membrane and increased the surface area... and blastocysts are not methylated, however, indicating that binding of CTCF is not required to establish...
MeSH term: ... transcript unexpectedly affects both the expression of all transcripts in the cluster and methylation of two... activity. CTCF maintains differential methylation at the Igf2/ H19 locus. When co- expressed, Dnmt1...
MeSH term: ... that the chromatin insulator protein CTCF carries a post- translational modification: poly( ADP- ribosyl) ation. Sequence analysis of GALNT3 identified biallelic deleterious mutations in all individuals with FTC...
Ornithorhynchus anatinus


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